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Jaak Vilo

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Articles 85
Citations 9873
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Recent Articles
1.
Talvik H, Oja M, Tamm S, Mooses K, Sarg D, Loo M, et al.
J Biomed Inform . 2024 Dec; 161():104765. PMID: 39732354
Objective: This study aims to address the gap in the literature on converting real-world Clinical Document Architecture (CDA) data into the Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM),...
2.
Haug M, Oja M, Pajusalu M, Mooses K, Reisberg S, Vilo J, et al.
J Am Med Inform Assoc . 2024 Mar; 31(5):1093-1101. PMID: 38472144
Objective: To introduce 2 R-packages that facilitate conducting health economics research on OMOP-based data networks, aiming to standardize and improve the reproducibility, transparency, and transferability of health economic models. Materials...
3.
Oja M, Tamm S, Mooses K, Pajusalu M, Talvik H, Ott A, et al.
JAMIA Open . 2023 Dec; 6(4):ooad100. PMID: 38058679
Objective: To describe the reusable transformation process of electronic health records (EHR), claims, and prescriptions data into Observational Medical Outcome Partnership (OMOP) Common Data Model (CDM), together with challenges faced...
4.
Kolberg L, Raudvere U, Kuzmin I, Adler P, Vilo J, Peterson H
Nucleic Acids Res . 2023 May; 51(W1):W207-W212. PMID: 37144459
g:Profiler is a reliable and up-to-date functional enrichment analysis tool that supports various evidence types, identifier types and organisms. The toolset integrates many databases, including Gene Ontology, KEGG and TRANSFAC,...
5.
Kurvits S, Harro A, Reigo A, Ott A, Laur S, Sarg D, et al.
Eur J Med Res . 2023 Mar; 28(1):133. PMID: 36966315
Background: Ischemic stroke (IS) is a major health risk without generally usable effective measures of primary prevention. Early warning signals that are easy to detect and widely available can save...
6.
Uuskula A, Oja M, Tamm S, Tisler A, Laanpere M, Padrik L, et al.
JAMA Netw Open . 2023 Feb; 6(2):e2254075. PMID: 36745455
Importance: Large-scale data on type-specific human papillomavirus (HPV) prevalence and disease burden worldwide are needed to guide cervical cancer prevention efforts. Promoting the research and application of health care big...
7.
Lepamets M, Auwerx C, Noukas M, Claringbould A, Porcu E, Kals M, et al.
HGG Adv . 2022 Aug; 3(4):100133. PMID: 36035246
Copy-number variations (CNV) are believed to play an important role in a wide range of complex traits, but discovering such associations remains challenging. While whole-genome sequencing (WGS) is the gold-standard...
8.
Hamid F, Alasoo K, Vilo J, Makeyev E
Methods Mol Biol . 2022 Jul; 2537:149-172. PMID: 35895263
Many eukaryotic genes can give rise to different alternative transcripts depending on stage of development, cell type, and physiological cues. Current transcriptome-wide sequencing technologies highlight the remarkable extent of this...
9.
Kunnapuu K, Ioannou S, Ligi K, Kolde R, Laur S, Vilo J, et al.
JAMIA Open . 2022 May; 5(1):ooac021. PMID: 35571357
Objective: To develop a framework for identifying temporal clinical event trajectories from Observational Medical Outcomes Partnership-formatted observational healthcare data. Materials And Methods: A 4-step framework based on significant temporal event...
10.
Kolberg L, Raudvere U, Kuzmin I, Vilo J, Peterson H
F1000Res . 2021 Feb; 9. PMID: 33564394
g:Profiler ( https://biit.cs.ut.ee/gprofiler) is a widely used gene list functional profiling and namespace conversion toolset that has been contributing to reproducible biological data analysis already since 2007. Here we introduce...