J W Forstrom
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Explore the profile of J W Forstrom including associated specialties, affiliations and a list of published articles.
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18
Citations
719
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Recent Articles
1.
Thrombopoietin accelerates platelet, red blood cell, and neutrophil recovery in myelosuppressed mice
Grossmann A, Lenox J, Ren H, HUMES J, Forstrom J, Kaushansky K, et al.
Exp Hematol
. 1996 Aug;
24(10):1238-46.
PMID: 8765500
The recent cloning of thrombopoietin (TPO) has allowed us to study its in vivo effects in normal and myelosuppressed mice. Normal Balb/c mice were treated with recombinant human TPO (hTPO)...
2.
Kaushansky K, Broudy V, Grossmann A, Humes J, Lin N, Ren H, et al.
J Clin Invest
. 1995 Sep;
96(3):1683-7.
PMID: 7657840
Thrombopoietin (TPO), the ligand for the receptor protooncogene c-mpl, has been cloned and shown to be the critical regulator of platelet production. Several features of c-Mpl expression, including its presence...
3.
Kaushansky K, Lok S, Holly R, Broudy V, Lin N, BAILEY M, et al.
Nature
. 1994 Jun;
369(6481):568-71.
PMID: 8202159
The development of blood cells including expansion of megakaryocyte progenitor cells requires the interplay of marrow stromal cells and polypeptide cytokines. Recently, characterization of c-Mpl, the receptor encoded by the...
4.
GOODMAN R, Foster D, Mathewes S, Osborn S, Kuijper J, Forstrom J, et al.
Biochemistry
. 1992 Nov;
31(43):10483-90.
PMID: 1420165
Alveolar macrophages (AM) mediate lung inflammation by producing lipid and peptide molecules that attract neutrophils (PMN) to the lung. Recently we described two porcine proteins called alveolar macrophage-derived chemotactic factors,...
5.
GOODMAN R, Forstrom J, Osborn S, Chi E, Martin T
J Biol Chem
. 1991 May;
266(13):8455-63.
PMID: 1850745
We have purified to homogeneity two distinct 10-kDa proteins with potent chemotactic activity for neutrophils from porcine alveolar macrophages incubated for 24 h with Escherichia coli endotoxin (lipopolysaccharide (LPS), 10...
6.
Hart C, Bailey M, Curtis D, Osborn S, Raines E, Ross R, et al.
Biochemistry
. 1990 Jan;
29(1):166-72.
PMID: 2322537
We have developed a panel of monoclonal antibodies to platelet-derived growth factor (PDGF) which have variable specificities for the three dimeric forms of the molecule (AA, AB, and BB). We...
7.
Two different subunits associate to create isoform-specific platelet-derived growth factor receptors
Seifert R, Hart C, Phillips P, Forstrom J, Ross R, Murray M, et al.
J Biol Chem
. 1989 May;
264(15):8771-8.
PMID: 2542288
Recent evidence has demonstrated that there is more than one form of platelet-derived growth factor (PDGF) receptor and that these receptors differ in their specificity for the multiple isoforms of...
8.
Hart C, Forstrom J, Kelly J, Seifert R, Smith R, Ross R, et al.
Science
. 1988 Jun;
240(4858):1529-31.
PMID: 2836952
Previous studies involving platelet-derived growth factor (PDGF) have been based on the premise that a single cell-surface receptor binds all three isoforms of PDGF (AA, BB, and AB). It is...
9.
Nelson K, George E, Swenson C, Forstrom J, Hellstrom K
J Immunol
. 1987 Sep;
139(6):2110-7.
PMID: 2957449
Hybridomas producing monoclonal antibodies (mAb) were obtained from BALB/c mice immunized against either of two transplanted, chemically induced syngeneic sarcomas, MCA-1490 or MCA-1511. Two mAb, 4.72 and 5.96, were obtained,...
10.
Kaushansky K, OHara P, Hart C, Forstrom J, Hagen F
Biochemistry
. 1987 Jul;
26(15):4861-7.
PMID: 3499177
cDNA clones for the human hematopoietic regulator granulocyte-macrophage colony-stimulating factor (hGM-CSF) were isolated from a lamba gt11 cDNA library prepared from RNA of COS cells transiently expressing the gene for...