J V Ravetch
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Explore the profile of J V Ravetch including associated specialties, affiliations and a list of published articles.
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112
Citations
9601
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Recent Articles
1.
Casey E, Bournazos S, Mo G, Mondello P, Tan K, Ravetch J, et al.
Leukemia
. 2017 Sep;
32(2):547-549.
PMID: 28924242
No abstract available.
2.
Durandy A, Kaveri S, Kuijpers T, Basta M, Miescher S, Ravetch J, et al.
Clin Exp Immunol
. 2009 Nov;
158 Suppl 1:2-13.
PMID: 19883419
High-dose intravenous immunoglobulin (IVIg) preparations are used currently for the treatment of autoimmune or inflammatory diseases. Despite numerous studies demonstrating efficacy, the precise mode of action of IVIg remains unclear....
3.
Hawiger D, Inaba K, Dorsett Y, Guo M, Mahnke K, Rivera M, et al.
J Exp Med
. 2001 Sep;
194(6):769-79.
PMID: 11560993
Dendritic cells (DCs) have the capacity to initiate immune responses, but it has been postulated that they may also be involved in inducing peripheral tolerance. To examine the function of...
4.
Guinamard R, Okigaki M, Schlessinger J, Ravetch J
Nat Immunol
. 2001 Mar;
1(1):31-6.
PMID: 10881171
The lymphoid organs contain specialized microanatomic structures composed of lymphoid, myeloid and stromal cells that are vital to the generation of an effective adaptive immune response. Although the existence of...
5.
Ravetch J, Bolland S
Annu Rev Immunol
. 2001 Mar;
19:275-90.
PMID: 11244038
Since the description of the first mouse knockout for an IgG Fc receptor seven years ago, considerable progress has been made in defining the in vivo functions of these receptors...
6.
Samuelsson A, Towers T, Ravetch J
Science
. 2001 Feb;
291(5503):484-6.
PMID: 11161202
The molecular basis for the anti-inflammatory property of intravenous gamma globulin (IVIG) was investigated in a murine model of immune thrombocytopenia. Administration of clinically protective doses of intact antibody or...
7.
Ravetch J, Lanier L
Science
. 2000 Oct;
290(5489):84-9.
PMID: 11021804
With the detailed description and analysis of several inhibitory receptor systems on lymphoid and myeloid cells, a central paradigm has emerged in which the pairing of activation and inhibition is...
8.
Bolland S, Ravetch J
Immunity
. 2000 Sep;
13(2):277-85.
PMID: 10981970
By virtue of its ability to couple the BCR to an inhibitory pathway, FcgammaRIIB can potentially determine the fate of B cells upon IgG immune complex engagement. We now provide...
9.
Qin D, Wu J, Vora K, Ravetch J, Szakal A, Manser T, et al.
J Immunol
. 2000 Jun;
164(12):6268-75.
PMID: 10843680
Generation of the B cell recall response appears to involve interaction of Ag, in the form of an immune complex (IC) trapped on follicular dendritic cells (FDCs), with germinal center...
10.
Clynes R, Towers T, Presta L, Ravetch J
Nat Med
. 2000 Mar;
6(4):443-6.
PMID: 10742152
Inhibitory receptors have been proposed to modulate the in vivo cytotoxic response against tumor targets for both spontaneous and antibody-dependent pathways. Using a variety of syngenic and xenograft models, we...