J V Ravetch
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Explore the profile of J V Ravetch including associated specialties, affiliations and a list of published articles.
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112
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9601
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Recent Articles
11.
Nakamura A, Yuasa T, Ujike A, Ono M, Nukiwa T, Ravetch J, et al.
J Exp Med
. 2000 Mar;
191(5):899-906.
PMID: 10704470
The combination of hemorrhagic pneumonitis and rapidly progressive glomerulonephritis is a characteristic feature of Goodpasture's syndrome (GPS), an autoimmune disease resulting from the interaction of pathogenic anti-collagen type IV (C-IV)...
12.
High pathogenic potential of low-affinity autoantibodies in experimental autoimmune hemolytic anemia
Fossati-Jimack L, Reininger L, Chicheportiche Y, Clynes R, Ravetch J, Honjo T, et al.
J Exp Med
. 1999 Dec;
190(11):1689-96.
PMID: 10587359
To assess the potency of low-affinity anti-red blood cell (RBC) autoantibodies in the induction of anemia, we generated an immunoglobulin (Ig)G2a class-switch variant of a 4C8 IgM anti-mouse RBC autoantibody,...
13.
Pearse R, Kawabe T, Bolland S, Guinamard R, Kurosaki T, Ravetch J
Immunity
. 1999 Jul;
10(6):753-60.
PMID: 10403650
Fc gammaRIIB is an inhibitory receptor that terminates activation signals initiated by antigen cross-linking of the BCR through the recruitment of SHIP. Fc gammaRIIB can also signal independently of BCR...
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15.
Ujike A, Ishikawa Y, Ono M, Yuasa T, Yoshino T, Fukumoto M, et al.
J Exp Med
. 1999 May;
189(10):1573-9.
PMID: 10330436
It is widely accepted that immunoglobulin (Ig)E triggers immediate hypersensitivity responses by activating a cognate high-affinity receptor, FcepsilonRI, leading to mast cell degranulation with release of vasoactive and proinflammatory mediators....
16.
Guinamard R, Signoret N, Ishiai M, Marsh M, Kurosaki T, Ravetch J, et al.
J Exp Med
. 1999 May;
189(9):1461-6.
PMID: 10224286
The entry of B lymphocytes into secondary lymphoid organs is a critical step in the development of an immune response, providing a site for repertoire shaping, antigen-induced activation and selection....
17.
Kubagawa H, Chen C, Ho L, Shimada T, Gartland L, Mashburn C, et al.
J Exp Med
. 1999 Jan;
189(2):309-18.
PMID: 9892613
PIR-A and PIR-B, paired immunoglobulin-like receptors encoded, respectively, by multiple Pira genes and a single Pirb gene in mice, are relatives of the human natural killer (NK) and Fc receptors....
18.
Yuasa T, Kubo S, Yoshino T, Ujike A, Matsumura K, Ono M, et al.
J Exp Med
. 1999 Jan;
189(1):187-94.
PMID: 9874575
Autoimmune diseases, like rheumatoid arthritis, result from a dysregulation of the immune response culminating in hyperactivation of effector cells leading to immune-mediated injury. To maintain an appropriate immune response and...
19.
Clynes R, Maizes J, Guinamard R, Ono M, Takai T, Ravetch J
J Exp Med
. 1999 Jan;
189(1):179-85.
PMID: 9874574
Autoantibodies and immune complexes are major pathogenic factors in autoimmune injury, responsible for initiation of the inflammatory cascade and its resulting tissue damage. This activation results from the interaction of...
20.
Okada H, Bolland S, Hashimoto A, Kurosaki M, Kabuyama Y, Iino M, et al.
J Immunol
. 1998 Nov;
161(10):5129-32.
PMID: 9820480
Src homology-2 domain-containing inositol polyphosphate 5'-phosphatase (SHIP) is a recently identified protein that has been implicated as an important signaling molecule. Although SHIP has been shown to participate in the...