J Thomas Cunningham
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Explore the profile of J Thomas Cunningham including associated specialties, affiliations and a list of published articles.
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70
Citations
1237
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Recent Articles
1.
Mabry S, Bradshaw J, Gardner J, Wilson E, Sunuwar J, Yeung H, et al.
Biol Sex Differ
. 2025 Jan;
16(1):5.
PMID: 39891225
Background: Obstructive sleep apnea (OSA) is an intermittent hypoxia disorder associated with cognitive dysfunction, including learning and memory impairments. There is evidence that alterations in protease activity and neuronal activation...
2.
Mabry S, Bradshaw J, Gardner J, Wilson E, Sunuwar J, Yeung H, et al.
Res Sq
. 2024 Dec;
PMID: 39711575
Background: Obstructive sleep apnea (OSA) is an intermittent hypoxia disorder associated with cognitive dysfunction, including learning and memory impairments. There is evidence that alterations in protease activity and neuronal activation...
3.
Farmer G, Cunningham J
Am J Physiol Regul Integr Comp Physiol
. 2024 Aug;
327(5):R486-R496.
PMID: 39133776
Angiotensin II (ANG II) has been shown to have central nervous system effects. Although tissue renin-angiotensin systems (RAS) have been demonstrated in multiple tissues, the existence of a brain RAS...
4.
Appiah C, Gardner J, Farmer G, Cunningham R, Cunningham J
Am J Physiol Regul Integr Comp Physiol
. 2024 Feb;
326(5):R333-R345.
PMID: 38406843
Obstructive sleep apnea, a common form of sleep-disordered breathing, is characterized by intermittent cessations of breathing that reduce blood oxygen levels and contribute to the development of hypertension. Hypertension is...
5.
Nguyen D, Duque V, Phillips N, Mecawi A, Cunningham J
Biol Sex Differ
. 2023 Oct;
14(1):71.
PMID: 37858270
Background: The supraoptic nucleus (SON) of the hypothalamus contains magnocellular neurosecretory cells that secrete the hormones vasopressin and oxytocin. Sex differences in SON gene expression have been relatively unexplored. Our...
6.
Aikins A, Farmer G, Little J, Cunningham J
J Neuroendocrinol
. 2023 Jun;
35(6):e13312.
PMID: 37337093
Dilutional hyponatremia due to increased plasma arginine vasopressin (AVP) is associated with liver cirrhosis. However, plasma AVP remains elevated despite progressive hypoosmolality. This study investigated changes to inhibitory control of...
7.
Jia S, Rybalchenko N, Kunwar K, Farmer Jr G, Little J, Toney G, et al.
J Neurophysiol
. 2022 Nov;
128(6):1383-1394.
PMID: 36321700
Chronic intermittent hypoxia (CIH), an animal model of sleep apnea, has been shown to alter the activity of second-order chemoreceptor neurons in the caudal nucleus of the solitary tract (cNTS)....
8.
Aikins A, Little J, Rybalchenko N, Cunningham J
Am J Physiol Regul Integr Comp Physiol
. 2022 Oct;
323(5):R797-R809.
PMID: 36189988
Dilutional hyponatremia associated with liver cirrhosis is due to inappropriate release of arginine vasopressin (AVP). Elevated plasma AVP causes water retention resulting in a decrease in plasma osmolality. Cirrhosis, in...
9.
Salvatore M, Soto I, Kasanga E, James R, Shifflet M, Doshier K, et al.
J Parkinsons Dis
. 2022 Jun;
12(6):1897-1915.
PMID: 35754287
Background: Rodent Parkinson's disease (PD) models are valuable to interrogate neurobiological mechanisms of exercise that mitigate motor impairment. Translating these mechanisms to human PD must account for physical capabilities of...
10.
Kasanga E, Little J, McInnis T, Bugnariu N, Cunningham J, Salvatore M
Front Aging Neurosci
. 2022 Jan;
13:775355.
PMID: 34975456
Preservation of motor capabilities is vital to maintaining independent daily living throughout a person's lifespan and may mitigate aging-related parkinsonism, a progressive and prevalent motor impairment. Physically active lifestyles can...