J S Owen
Overview
Explore the profile of J S Owen including associated specialties, affiliations and a list of published articles.
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108
Citations
577
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Recent Articles
1.
Santos M, Canuto K, de Aquino C, Martins C, Brito G, Pessoa T, et al.
Braz J Med Biol Res
. 2020 May;
53(6):e9031.
PMID: 32401929
Malnutrition is still considered endemic in many developing countries. Malnutrition-enteric infections may cause lasting deleterious effects on lipid metabolism, especially in children living in poor settings. The regional basic diet...
2.
Mclean D, Meers L, Ralph J, Owen J, Small A
Res Vet Sci
. 2017 Jan;
112:13-17.
PMID: 28107666
Stunning prior to slaughter is commonly used to render the animal insensible to pain. However, for certain markets, stunning is disallowed, unless the animal can fully recover if not slaughtered....
3.
Hassall D, Desai K, Owen J, Bruckdorfer K
Platelets
. 2010 Nov;
1(1):29-35.
PMID: 21043983
Sensitisation of human blood platelets by plasma low-density lipoproteins (LDL) is thought to involve an initial interaction between LDL and the platelet surface membrane. When washed, fully responsive platelets were...
4.
Pai A, Nielsen J, Kausz A, Miller P, Owen J
Clin Pharmacol Ther
. 2010 Jul;
88(2):237-42.
PMID: 20592725
Intravenous (IV) iron is used to treat iron-deficiency anemia in patients with chronic kidney disease (CKD). Ferumoxytol is a novel iron formulation administered rapidly as two IV boluses of 510...
5.
Disterer P, Simons J, Owen J
Gene Ther
. 2009 Apr;
16(6):824-6.
PMID: 19340016
Several independent groups have reported targeted genomic editing in mammalian cells mediated by synthetic oligonucleotides. Nevertheless, the validity of data has been disputed because of experimental artefacts, inconsistent findings and...
6.
O Meara C, Hanrahan J, Prathalingam N, Owen J, Donovan A, Fair S, et al.
Theriogenology
. 2008 Feb;
69(4):513-22.
PMID: 18248736
Several procedures have been proposed to assess structural and functional characteristics of cryopreserved ram semen but none so far have yielded consistent relationships with in vivo fertility. The objectives of...
7.
Van Wart S, Cirincione B, Ludwig E, Meagher A, Korth-Bradley J, Owen J
J Clin Pharmacol
. 2007 May;
47(6):727-37.
PMID: 17519399
Tigecycline, a novel glycylcycline, possesses broad-spectrum antimicrobial activity. A structural population pharmacokinetic model for tigecycline was developed based on data pooled from 5 phase I studies. Intravenous tigecycline was administered...
8.
Van Wart S, Owen J, Ludwig E, Meagher A, Korth-Bradley J, Cirincione B
Antimicrob Agents Chemother
. 2006 Aug;
50(11):3701-7.
PMID: 16940069
Tigecycline, a first-in-class expanded glycylcycline antimicrobial agent, has demonstrated efficacy in the treatment of complicated skin and skin structure infections (cSSSI) and complicated intra-abdominal (cIAI) infections. A population pharmacokinetic (PK)...
9.
Facundo H, Brandt C, Owen J, Lima V
Braz J Med Biol Res
. 2004 Jul;
37(7):957-62.
PMID: 15264001
Schistosoma mansoni causes liver disease by inducing granulomatous inflammation. This favors formation of reactive oxygen species, including superoxide ions, hydrogen peroxide and hydroxyl radicals all of which may induce lipid...
10.
Harris J, Schepelmann S, Athanasopoulos T, Graham I, Stannard A, Mohri Z, et al.
Gene Ther
. 2002 Feb;
9(1):21-9.
PMID: 11850719
Apolipoprotein E (apoE) is a multifunctional plasma glycoprotein involved in lipoprotein metabolism and a range of cell signalling phenomena. ApoE-deficient (apoE(-/-)) mice exhibit severe hypercholesterolaemia and are an excellent model...