J S Dileep Kumar
Overview
Explore the profile of J S Dileep Kumar including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
60
Citations
760
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Dileep Kumar J, Molotkov A, Carberry P, Chaly T, Neelamegam R, Mintz A
Bioorg Med Chem Lett
. 2022 Aug;
74:128941.
PMID: 35964845
Combinations of antiangiogenic and cytotoxic agents show promising results in the treatment of cancer. However, there is a lack of single agent with both antiangiogenic and cytotoxic activities for clinical...
2.
Dileep Kumar J, Molotkov A, Kim J, Carberry P, Idumonyi S, Castrillon J, et al.
Pharmacol Rep
. 2022 Mar;
74(3):539-544.
PMID: 35286710
Background: Microtubules are abundant in brain and their malfunctioning occurs in the early-to-advanced stages of neurodegenerative disorders. At present, there is no in vivo test available for a definitive diagnosis...
3.
Dileep Kumar J, Molotkov A, Salling M, Carberry P, Prabhakaran J, Castrillon J, et al.
Pharmacol Rep
. 2021 Sep;
74(1):241-247.
PMID: 34491568
Background: Excessive alcohol consumption is a global health burden and requires a better understanding of its neurobiology. A lower density of brain microtubules is found in alcohol-related human brain disease...
4.
Dileep Kumar J, Prabhakaran J, Molotkov A, Sattiraju A, Kim J, Doubrovin M, et al.
Pharmacol Rep
. 2020 Jul;
72(5):1433-1440.
PMID: 32632914
Background: The upregulation of cyclooxygenase-2 (COX-2) is involved in neuroinflammation associated with many neurological diseases as well as cancers of the brain. Outside the brain, inflammation and COX-2 induction contribute...
5.
Narayanaswami V, Tong J, Fiorino F, Severino B, Sparaco R, Magli E, et al.
EJNMMI Radiopharm Chem
. 2020 May;
5(1):13.
PMID: 32430632
Background: Serotonin 1A (5-HT) receptors are implicated in the pathogenesis of several psychiatric and neurodegenerative disorders motivating the development of suitable radiotracers for in vivo positron emission tomography (PET) neuroimaging....
6.
Dileep Kumar J, Prabhakaran J, Damuka N, Hines J, Norman S, Dodda M, et al.
Bioorg Med Chem Lett
. 2019 Nov;
30(2):126785.
PMID: 31753695
Altered dynamics of microtubules (MT) are implicated in the pathophysiology of a number of brain diseases. Therefore, radiolabeled MT targeted ligands that can penetrate the blood brain barrier (BBB) may...
7.
Prabhakaran J, Sai K, Sattiraju A, Mintz A, Mann J, Dileep Kumar J
Bioorg Med Chem Lett
. 2019 Feb;
29(6):778-781.
PMID: 30709652
Dysfunction of GSK3 is implicated in the etiology of many brain, inflammatory, cardiac diseases, and cancer. PET imaging would enable in vivo detection and quantification of GSK3 and can impact...
8.
Sherin D, Geethu C, Prabhakaran J, Mann J, Dileep Kumar J, Manojkumar T
Comput Biol Chem
. 2018 Dec;
78:108-115.
PMID: 30502727
Serotonin receptor, 5-HTR, agonists and partial agonists have established drug candidates for psychiatric and neurologic disorders. Recently, we reported the synthesis and evaluation of arylpiperazine derivatives of 3,5-dioxo-(2H,4H)-1,2,4-triazine as 5-HTR...
9.
Dileep Kumar J, Zanderigo F, Prabhakaran J, Rubin-Falcone H, Parsey R, Mann J
Bioorg Med Chem Lett
. 2018 Nov;
28(23-24):3592-3595.
PMID: 30396759
Overexpression of Cyclooxygenase-2 (COX-2) enzyme is associated with the pathogenesis of inflammation, cancers, stroke, arthritis, and neurological disorders. Because of the involvement of COX-2 in these diseases, quantification of COX-2...
10.
Dileep Kumar J, Bai B, Zanderigo F, DeLorenzo C, Prabhakaran J, Parsey R, et al.
Molecules
. 2018 Aug;
23(8).
PMID: 30072617
COX-2 selective inhibitors (COXIBs) are non-steroidal anti-inflammatory drugs (NSAIDs), with fewer side effects compared with non-selective NSAIDs, and are used for the treatment of arthritis, headaches, and other inflammatory diseases...