J R Starkey
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Explore the profile of J R Starkey including associated specialties, affiliations and a list of published articles.
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38
Citations
494
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Recent Articles
1.
Kazmin D, Hoyt T, Taubner L, Teintze M, Starkey J
J Mol Biol
. 2000 Apr;
298(3):431-45.
PMID: 10772861
We utilized a 9-mer random phage display library to identify sequences which bind to laminin-1 and elute with heparan sulfate or peptide 11 (CDPGYIGSR). Laminin-1 derivatized plates were used for...
2.
Starkey J, Uthayakumar S, Berglund D
Cytometry
. 1999 Nov;
35(1):37-47.
PMID: 10554179
Background: Peptide 11, a nine-amino acid sequence from the beta1 chain of laminin-1, has been reported to inhibit tumor cell invasion of basement membranes, and to reduce tumor lung colonization...
3.
Starkey J, Dai S, Dratz E
Biochim Biophys Acta
. 1999 Jan;
1429(1):187-207.
PMID: 9920396
The structure of laminin peptide 11 (CDPGYIGSR-NH2) contains valuable information for the design of mimetic compounds with anti-invasive and anti-metastatic properties. An alanine scan replacement experiment identified Tyr5, Ile6 and...
4.
Schweitzer M, Marshall M, Carron K, Bohle D, Busse S, Arnold E, et al.
Proc Natl Acad Sci U S A
. 1997 Jun;
94(12):6291-6.
PMID: 9177210
Six independent lines of evidence point to the existence of heme-containing compounds and/or hemoglobin breakdown products in extracts of trabecular tissues of the large theropod dinosaur Tyrannosaurus rex. These include...
5.
Landowski T, Dratz E, Starkey J
Biochemistry
. 1995 Sep;
34(35):11276-87.
PMID: 7669786
The level of expression of the 67 kDa high-affinity laminin binding protein (LBP) correlates with the progression of many solid tumors. The cDNA clone for the 67 kDa LBP is...
6.
Landowski T, Uthayakumar S, Starkey J
Clin Exp Metastasis
. 1995 Sep;
13(5):357-72.
PMID: 7641420
A number of papers have been published on the clinical correlation of the expression of the 67 kDa laminin binding protein (LBP) with the metastatic potential of solid tumors. Both...
7.
Elstad C, Meadows G, Aslakson C, Starkey J
Adv Exp Med Biol
. 1994 Jan;
354:171-83.
PMID: 7520663
We have shown that Tyr and Phe restriction suppresses the malignant phenotype of the highly invasive and metastatic BL6 variant of B16 murine melanoma. Lung-colonizing abilities of Tyr- and Phe-modulated...
8.
Ostheimer G, Starkey J, Lambert C, Helgerson S, Dratz E
J Biol Chem
. 1992 Dec;
267(35):25120-8.
PMID: 1460013
Peptide 11, CDPGYIGSR-NH2, is a segment of laminin which blocks tumor cell invasion. A high affinity laminin receptor in tumor cells is thought to be blocked by the carboxyl-terminal YIGSR,...
9.
Berglund D, Starkey J
Cytometry
. 1991 Jan;
12(1):64-7.
PMID: 1999124
Conditions for labelling an intracellular antigen, p21ras, using electroporation to introduce a fluorescent antibody, are described. Following labelling, cells were evaluated for p21ras associated fluorescence by flow cytometry. Electroporation, sorting,...
10.
Starkey J
Cancer Metastasis Rev
. 1990 Sep;
9(2):113-23.
PMID: 2253311
This manuscript reviews the molecular aspects of tumor cell invasion of extracellular matrix. The changes in cell:substrate and cell:cell receptors that characterize motile cells are discussed for their importance not...