J R Didsbury
Overview
Explore the profile of J R Didsbury including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
17
Citations
894
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Miagkov A, Kovalenko D, Brown C, Didsbury J, Cogswell J, Stimpson S, et al.
Proc Natl Acad Sci U S A
. 1998 Nov;
95(23):13859-64.
PMID: 9811891
The transcription factor NF-kappaB is a pivotal regulator of inflammatory responses. While the activation of NF-kappaB in the arthritic joint has been associated with rheumatoid arthritis (RA), its significance is...
2.
Moss M, Jin S, Milla M, Bickett D, Burkhart W, Carter H, et al.
Nature
. 1997 Feb;
385(6618):733-6.
PMID: 9034191
Tumour-necrosis factor-alpha (TNF-alpha) is a cytokine that contributes to a variety of inflammatory disease states. The protein exists as a membrane-bound precursor of relative molecular mass 26K which can be...
3.
Tomhave E, Richardson R, Didsbury J, Menard L, Snyderman R, Ali H
J Immunol
. 1994 Oct;
153(7):3267-75.
PMID: 8089498
The formylpeptide (fMLP) and C5a chemoattractants were previously shown to cross-desensitize each other's ability to mobilize Ca2+ in leukocytes but not to affect nonchemoattractant Ca(2+)-mobilizing receptors, and vice versa. Our...
4.
Ali H, Richardson R, Tomhave E, Didsbury J, Snyderman R
J Biol Chem
. 1993 Nov;
268(32):24247-54.
PMID: 8226971
To define the regulation of chemoattractant receptors, epitope-tagged human formyl peptide and C5a receptor cDNAs (ET-FR and ET-C5aR) were stably expressed in rat basophilic leukemia, RBL-2H3 cells. An antibody (12CA5)...
5.
Menard L, Tomhave E, Casey P, Uhing R, Snyderman R, Didsbury J
Eur J Biochem
. 1992 Jun;
206(2):537-46.
PMID: 1597193
Rac1, a member of the family of low-molecular-mass GTP-binding proteins, functions in phagocytic leukocytes as a component necessary for activation of the respiratory burst. To characterize the biochemical properties of...
6.
Just I, Mohr C, Schallehn G, Menard L, Didsbury J, Vandekerckhove J, et al.
J Biol Chem
. 1992 May;
267(15):10274-80.
PMID: 1587816
We purified a novel ADP-ribosyltransferase produced by a Clostridium limosum strain isolated from a lung abscess and compared the exoenzyme with Clostridium botulinum ADP-ribosyltransferase C3. The C. limosum exoenzyme has...
7.
Uhing R, Gettys T, Tomhave E, Snyderman R, Didsbury J
Biochem Biophys Res Commun
. 1992 Mar;
183(3):1033-9.
PMID: 1314571
Endogenous neutrophil formylpeptide receptors do not inhibit adenylylcyclase activation. The ability of a cloned and transfected human formylpeptide receptor to mediate the inhibition of adenylylcyclase was assessed in the human...
8.
Didsbury J, Uhing R, Tomhave E, Gerard C, Gerard N, Snyderman R
FEBS Lett
. 1992 Feb;
297(3):275-9.
PMID: 1544408
Human kidney 293 TSA cells were transfected by a calcium phosphate method with human formylpeptide and C5a receptor cDNAs with high efficiency. Formylpeptide receptor positive transfectants expressed a total of...
9.
Didsbury J, Uhing R, Tomhave E, Gerard C, Gerard N, Snyderman R
Proc Natl Acad Sci U S A
. 1991 Dec;
88(24):11564-8.
PMID: 1763071
To better define their regulation, formylpeptide and C5a chemoattractant receptor cDNAs were transiently expressed with high efficiency (approximately 35-54%) in human kidney cells. As in neutrophils, both receptors were active...
10.
Didsbury J, Uhing R, Snyderman R
Biochem Biophys Res Commun
. 1990 Sep;
171(2):804-12.
PMID: 2119580
Ras proteins can be modified at their COOH-terminal cysteine in the motif Cys-Ali-Ali-Xaa by a farnesyl isoprenoid. This modification is essential for membrane association and biological activity of ras proteins....