J P Shaw
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Explore the profile of J P Shaw including associated specialties, affiliations and a list of published articles.
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77
Citations
1439
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Recent Articles
1.
Moore M, Shaw J, Pascoe C, Beesley A, Viarengo A, Lowe D
Mar Environ Res
. 2020 Feb;
156:104903.
PMID: 32056801
This investigation using a molluscan animal model tested the hypothesis that experimentally induced lysosomal autophagy protects against oxidative cell injury. Induction of augmented lysosomal autophagy has previously been implicated in...
2.
Shaw J, Moore M, Readman J, Mou Z, Langston W, Lowe D, et al.
Mar Environ Res
. 2019 Nov;
152:104825.
PMID: 31668363
Autophagy is a highly conserved evolutionary survival or defence process that enables cells and organisms to survive periods of environmental stress by breaking down cellular organelles and macromolecules in autolysosomes...
3.
4.
Shaw J, Dondero F, Moore M, Negri A, Dagnino A, Readman J, et al.
Mar Environ Res
. 2011 Jun;
72(1-2):13-24.
PMID: 21683998
The aim of this study was to examine whether a combination of biochemical, histopathological and toxicogenomic data could be used as a valuable tool for the assessment of biological risk...
5.
McKinnell R, Armstrong S, Beattie D, Choi S, Fatheree P, Gendron R, et al.
J Med Chem
. 2009 Aug;
52(17):5330-43.
PMID: 19663444
5-HT(4) receptor agonists such as tegaserod have demonstrated efficacy in the treatment of constipation predominant irritable bowel syndrome (IBS-C), a highly prevalent disorder characterized by chronic constipation and impairment of...
6.
Gauld N, Shaw J, Emmerton L, Pethica B
Pharmacoepidemiol Drug Saf
. 2008 Nov;
9(3):207-14.
PMID: 19025821
Purpose: Postmarketing surveillance of prescription medicines is a routine practice, yet similar evaluation of non-prescription medicines, including those recently switched from prescription status, is uncommon. This study presents the methodologic...
7.
Smith J, Beattie D, Marquess D, Shaw J, Vickery R, Humphrey P
Naunyn Schmiedebergs Arch Pharmacol
. 2008 Apr;
378(1):125-37.
PMID: 18415081
The in vitro pharmacological profile of TD-5108, a novel, selective 5-HT(4) receptor agonist, was compared to that of clinically efficacious gastroprokinetic 5-HT(4) receptor agonists. TD-5108 produced an elevation of cyclic...
8.
Beattie D, Armstrong S, Shaw J, Marquess D, Sandlund C, Smith J, et al.
Naunyn Schmiedebergs Arch Pharmacol
. 2008 Apr;
378(1):139-47.
PMID: 18408918
The in vivo preclinical pharmacodynamic profile of TD-5108, a selective 5-HT(4) receptor agonist with high intrinsic activity, was compared to that of the clinically studied gastrointestinal pro-kinetic agents, tegaserod, cisapride...
9.
Shaw J, Seroogy J, Kaniga K, Higgins D, Kitt M, Barriere S
Antimicrob Agents Chemother
. 2004 Dec;
49(1):195-201.
PMID: 15616296
The pharmacokinetics, tolerability, and serum inhibitory and bactericidal titers of telavancin, a new rapidly bactericidal lipoglycopeptide with multiple mechanisms of action against gram-positive pathogens, were assessed in a two-part, randomized,...
10.
Shaw J, Large A, Donkin P, Evans S, Staff F, Livingstone D, et al.
Aquat Toxicol
. 2004 Apr;
67(4):325-36.
PMID: 15084409
The relationship between cytochrome P450 1A- and 2E-immunopositive proteins, lipid peroxidation and DNA strand breaks (SBs) was studied in Mytilus edulis digestive gland at different seasons and at different sites...