J P Odonnell
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Explore the profile of J P Odonnell including associated specialties, affiliations and a list of published articles.
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96
Citations
313
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Recent Articles
21.
22.
Flowers N, Odonnell J, Colby H
Drug Metab Dispos
. 1989 Mar;
17(2):186-9.
PMID: 2565209
Prior investigations demonstrated that many of the actions of spironolactone (SL) required deacetylation of the parent compound as the first step in the formation of biologically active metabolites. Studies were...
23.
Odonnell J, Radtke R, Leicht D, Caesar R
J Gen Psychol
. 1988 Oct;
115(4):355-68.
PMID: 3209998
Using a multi-trial, free-recall paradigm (Rey Auditory-Verbal Learning Test; Lezak, 1983), the acquisition and retention by learning disabled (LD) young adults with a Halstead Impairment Index less than or equal...
24.
Flowers N, Sherry J, Odonnell J, Colby H
Biochem Pharmacol
. 1988 Apr;
37(8):1591-5.
PMID: 3358788
Previous investigations have established that spironolactone (SL) administration to guinea pigs decreases adrenal mitochondrial and microsomal cytochrome P-450 content, and that the latter requires microsomal activation of the drug. Studies...
25.
Phonetically inaccurate spelling among learning-disabled, head-injured, and nondisabled young adults
Horn J, Odonnell J, Leicht D
Brain Lang
. 1988 Jan;
33(1):55-64.
PMID: 2449261
We applied the Boder and Jarrico (1982, The Boder Test of Reading-Spelling Patterns, New York: Grune & Stratton) criteria to the WRAT spelling list and examined the phonetically inaccurate spelling...
26.
LaCagnin L, Colby H, Dalal N, Odonnell J
Biochem Pharmacol
. 1987 Aug;
36(16):2667-72.
PMID: 3038130
There is evidence to suggest that the oxidative metabolism of hydralazine (HP), an antihypertensive drug, may represent a toxic pathway which could account for some of the adverse effects of...
27.
Chaturvedi P, Odonnell J, Nicholas J, Shoenthal D, Waters D, Gwilt P
Int J Clin Pharmacol Ther Toxicol
. 1987 Mar;
25(3):123-8.
PMID: 3557737
Furosemide, a potent loop diuretic, is commonly used in the treatment of congestive heart failure (CHF). Unpredictability in the diuretic effect following oral doses has been attributed to variable and...
28.
Fedan J, Hogaboom G, Odonnell J
Eur J Pharmacol
. 1986 Oct;
129(3):279-91.
PMID: 3780845
Some structural requirements which are important for the contractile activity of adenine nucleotides at P2-purinergic receptors in the guinea-pig isolated vas deferens were examined. The consequences of deletions, substitutions and...
29.
LaCagnin L, Colby H, Odonnell J
Drug Metab Dispos
. 1986 Sep;
14(5):549-54.
PMID: 2876860
Previous observations have demonstrated a relationship between the toxicity of the antihypertensive drug, hydralazine (HP), and acetylator phenotype, suggesting a role for metabolism in the adverse effects of HP. Experiments...
30.
LaCagnin L, Colby H, Odonnell J
J Chromatogr
. 1986 Apr;
377:319-27.
PMID: 3711222
A selective high-performance liquid chromatographic assay for the separation and quantitation of the proposed hepatic microsomal metabolites of hydralazine (HP), phthalazine, phthalazinone, s-triazolo[3,4-a]phthalazine, 3-methyl-s-triazolo[3,4-a]phthalazine and 3-hydroxymethyl-s-triazolo [3,4-a]phthalazine, is described. An...