J O Vigoreaux
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Explore the profile of J O Vigoreaux including associated specialties, affiliations and a list of published articles.
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16
Citations
473
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Recent Articles
1.
Vigoreaux J
Bioessays
. 2001 Dec;
23(11):1047-63.
PMID: 11746221
This essay reviews the long tradition of experimental genetics of the Drosophila indirect flight muscles (IFM). It discusses how genetics can operate in tandem with multidisciplinary approaches to provide a...
2.
Reedy M, Bullard B, Vigoreaux J
J Cell Biol
. 2001 Jan;
151(7):1483-500.
PMID: 11134077
Flightin is a multiply phosphorylated, 20-kD myofibrillar protein found in Drosophila indirect flight muscles (IFM). Previous work suggests that flightin plays an essential, as yet undefined, role in normal sarcomere...
3.
Vigoreaux J, Moore J, Maughan D
Adv Exp Med Biol
. 2000 Sep;
481:237-47; discussion 247-50.
PMID: 10987076
We examine how the stretch activation response of the Drosophila indirect flight muscles (IFM) is affected by the projectin mutation bentDominant. IFM from flies heterozygous for this mutation (bentD/+) produce...
4.
Moore J, Vigoreaux J, Maughan D
J Muscle Res Cell Motil
. 2000 Mar;
20(8):797-806.
PMID: 10730582
Projectin is a ca. 900 kDa protein that is a member of the titin protein superfamily. In skeletal muscle titins are involved in the longitudinal reinforcement of the sarcomere by...
5.
Moore J, Dickinson M, Vigoreaux J, Maughan D
Biophys J
. 2000 Feb;
78(3):1431-40.
PMID: 10692328
The Drosophila myosin regulatory light chain (DMLC2) is homologous to MLC2s of vertebrate organisms, except for the presence of a unique 46-amino acid N-terminal extension. To study the role of...
6.
Vigoreaux J, Hernandez C, Moore J, Ayer G, Maughan D
J Exp Biol
. 1998 Jun;
201(Pt 13):2033-44.
PMID: 9622575
We have developed a reverse-genetic approach to study the function of flightin, a unique protein of the flight muscle myofibril of Drosophila melanogaster. We describe the generation and characterization of...
7.
Dickinson M, Hyatt C, Lehmann F, Moore J, Reedy M, Simcox A, et al.
Biophys J
. 1997 Dec;
73(6):3122-34.
PMID: 9414224
We examine how the structure and function of indirect flight muscle (IFM) and the entire flight system of Drosophila melanogaster are affected by phosphorylation of the myosin regulatory light chain...
8.
Kronert W, ODonnell P, Fieck A, Lawn A, Vigoreaux J, Sparrow J, et al.
J Mol Biol
. 1995 May;
249(1):111-25.
PMID: 7776366
We have determined the molecular and ultrastructural defects associated with three homozygous-viable myosin heavy chain mutations of Drosophila melanogaster. These mutations cause a dominant flightless phenotype but allow relatively normal...
9.
Vigoreaux J, Perry L
J Muscle Res Cell Motil
. 1994 Dec;
15(6):607-16.
PMID: 7706417
Drosophila stretch-activated flight muscles contain flightin, a novel myofibrillar protein that interacts with myosin filaments. We have identified eleven flightin isoelectric variants that can be subdivided into phosphorylated and non-phosphorylated...
10.
Vigoreaux J
Biochem Genet
. 1994 Aug;
32(7-8):301-14.
PMID: 7826316
Flightin is a 20-kD myofibrillar protein found in the stretch-activated flight muscles of Drosophila melanogaster. Nine of the eleven isoelectric variants of flightin are generated in vivo by multiple phosphorylations....