J Michael Sorrell
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Explore the profile of J Michael Sorrell including associated specialties, affiliations and a list of published articles.
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16
Citations
646
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Recent Articles
1.
Sorrell J, Caplan A
Biomedicines
. 2022 Sep;
10(9).
PMID: 36140217
White adipose tissues are major endocrine organs that release factors, termed adipokines, which affect other major organ systems. The development and functions of adipose tissues depend largely upon the glycosaminoglycan...
2.
Sorrell J, Somoza R, Caplan A
J Orthop Res
. 2017 Dec;
36(6):1757-1766.
PMID: 29194731
Regenerative medicine and tissue engineering studies are actively developing novel means to repair adult articular cartilage defects using biological approaches. One such approach is the harnessing of adult human therapeutic...
3.
Caplan A, Sorrell J
Immunol Lett
. 2015 Jun;
168(2):136-9.
PMID: 26079607
We have evolved cellular mechanisms for protecting us from disabling intruders or injuries. The Mesenchymal Stem Cell, MSC, is derived from perivascular cells, pericytes that are liberated from their basement...
4.
Sorrell J, Baber M, Traktuev D, March K, Caplan A
Biomaterials
. 2011 Oct;
32(36):9667-76.
PMID: 21959010
An increased demand for soft-tissue substitutes has impelled the development of an in vitro adipose tissue. Ideally, such a tissue should contain a vascular network that can deliver blood throughout...
5.
Carrino D, Calabro A, Darr A, Dours-Zimmermann M, Sandy J, Zimmermann D, et al.
Glycobiology
. 2010 Oct;
21(2):257-68.
PMID: 20947661
Previous work has shown that versican, decorin and a catabolic fragment of decorin, termed decorunt, are the most abundant proteoglycans in human skin. Further analysis of versican indicates that four...
6.
Sorrell J, Caplan A
Stem Cell Res Ther
. 2010 Sep;
1(4):30.
PMID: 20863417
Mesenchymal stem cells are a heterogeneous population of fibroblast-like cells found in most adult organs. However, most of our current knowledge is based on cells of bone marrow or interstitial...
7.
Sorrell J, Caplan A
Int Rev Cell Mol Biol
. 2009 Jul;
276:161-214.
PMID: 19584013
The capacity of fibroblasts to produce and organize the extracellular matrix and to communicate with other cells makes them a central component of tissue biology. Even so, fibroblasts remain a...
8.
Sorrell J, Baber M, Caplan A
Tissue Eng Part A
. 2009 Feb;
15(7):1751-61.
PMID: 19196139
The effective delivery of bioactive molecules to wound sites hasten repair. Cellular therapies provide a means for the targeted delivery of a complex, multiple arrays of bioactive factors to wound...
9.
Sorrell J, Baber M, Caplan A
Wound Repair Regen
. 2008 Mar;
16(2):300-9.
PMID: 18318814
The superficial dermis of adult human skin contains a complex arcading microvasculature that provides nutrient support to the overlying epidermis. We propose that the unique subpopulations of dermal fibroblasts located...
10.
Sorrell J, Baber M, Caplan A
Cells Tissues Organs
. 2007 Jul;
186(3):157-68.
PMID: 17657137
The construction of vascularized connective tissues is an important goal in tissue engineering in that the presence of a patent bio-engineered vasculature should facilitate vascularization of an implant. Fibroblasts play...