J Marie Hardwick
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Explore the profile of J Marie Hardwick including associated specialties, affiliations and a list of published articles.
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88
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6089
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Recent Articles
1.
Jacobs E, Dragotakes Q, Kulkarni M, Dziedzic A, Jedlicka A, Hardwick J, et al.
bioRxiv
. 2024 Dec;
PMID: 39677607
Gene knockout strain collections are important tools for discovery in microbiology. is the only human pathogenic fungus with an available genome-wide deletion collection, and this resource is widely used by...
2.
Francis V, Liddle C, Camacho E, Kulkarni M, Junior S, Harvey J, et al.
mBio
. 2024 Mar;
15(4):e0307823.
PMID: 38511961
causes lethal meningitis and accounts for approximately 10%-15% of AIDS-associated deaths worldwide. There are major gaps in our understanding of how this fungus invades the mammalian brain. To investigate the...
3.
Francis V, Liddle C, Camacho E, Kulkarni M, Junior S, Harvey J, et al.
bioRxiv
. 2023 Nov;
PMID: 38014111
The fungus causes lethal meningitis in humans with weakened immune systems and is estimated to account for 10-15% of AIDS-associated deaths worldwide. There are major gaps in our understanding of...
4.
Kulkarni M, Hardwick J
Annu Rev Genet
. 2023 Sep;
57:435-459.
PMID: 37722687
Programmed cell death (self-induced) is intrinsic to all cellular life forms, including unicellular organisms. However, cell death research has focused on animal models to understand cancer, degenerative disorders, and developmental...
5.
Vitale I, Pietrocola F, Guilbaud E, Aaronson S, Abrams J, Adam D, et al.
Cell Death Differ
. 2023 Apr;
30(5):1097-1154.
PMID: 37100955
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis in mammalian systems have...
6.
Sephton-Clark P, McConnell S, Grossman N, Baker R, Dragotakes Q, Fan Y, et al.
Proc Natl Acad Sci U S A
. 2023 Jan;
120(2):e2217111120.
PMID: 36603033
A pet cockatoo was the suspected source of recovered from an immunocompromised patient with cryptococcosis based on molecular analyses available in 2000. Here, we report whole genome sequence analysis of...
7.
Smith D, Dragotakes Q, Kulkarni M, Hardwick J, Casadevall A
Commun Biol
. 2022 Dec;
5(1):1364.
PMID: 36510005
A key component of the insect immune response is melanin production, including within nodules, or aggregations of immune cells surrounding microbes. Melanization produces oxidative and toxic intermediates that limit microbial...
8.
Stolp Z, Kulkarni M, Liu Y, Zhu C, Jalisi A, Lin S, et al.
Cell Rep
. 2022 Apr;
39(2):110647.
PMID: 35417721
Unicellular eukaryotes have been suggested as undergoing self-inflicted destruction. However, molecular details are sparse compared with the mechanisms of programmed/regulated cell death known for human cells and animal models. Here,...
9.
Hardwick J, Knorre D, Palkova Z, Winderickx J
Front Cell Dev Biol
. 2022 Jan;
9:823447.
PMID: 35059403
No abstract available.
10.
Lamb H, Hardwick J
Mol Cell
. 2019 Sep;
75(6):1087-1089.
PMID: 31539505
The role of hormones in triggering cell death has been controversial. In this issue of Molecular Cell, Li et al. (2019) have defined a molecular pathway where an unexpected estrogen...