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J Lindenbaum

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11.
Naurath H, Joosten E, Riezler R, Stabler S, Allen R, Lindenbaum J
Lancet . 1995 Jul; 346(8967):85-9. PMID: 7603218
In a prospective, multicentre, double-blind controlled study, the effect of an intramuscular vitamin supplement containing 1 mg vitamin B12, 1.1 mg folate, and 5 mg vitamin B6 on serum concentrations...
12.
Lindenbaum J, Healton E, Savage D, Brust J, Garrett T, Podell E, et al.
Nutrition . 1995 Mar; 11(2):181; discussion 180, 182. PMID: 7647490
No abstract available.
13.
Allen R, Lindenbaum J, Stabler S
Trans Am Clin Climatol Assoc . 1995 Jan; 107:37-45; discussion 45-7. PMID: 8725558
In summary, we have shown that there is a high prevalence of Cbl deficiency in the elderly. This observation is based on an increase in the number of low and...
14.
Lindenbaum J, Rosenberg I, Wilson P, Stabler S, Allen R
Am J Clin Nutr . 1994 Jul; 60(1):2-11. PMID: 8017332
To determine whether the increased prevalence of low serum cobalamin concentrations in elderly people represents true deficiency, serum concentrations of cobalamin and folate and of metabolites that are sensitive indicators...
15.
Savage D, Gangaidzo I, Lindenbaum J, Kiire C, Mukiibi J, Moyo A, et al.
Br J Haematol . 1994 Apr; 86(4):844-50. PMID: 7880241
In a study of the pathogenesis and clinical features of megaloblastic anaemia in southern Africa, we evaluated 144 consecutive Zimbabwean patients with megaloblastic haemopoiesis. Vitamin B12 deficiency was diagnosed in...
16.
Savage D, Lindenbaum J, Stabler S, Allen R
Am J Med . 1994 Mar; 96(3):239-46. PMID: 8154512
Purpose: Patients with cobalamin (vitamin B12) deficiency usually lack many of the classic features of severe megaloblastic anemia; because of the low diagnostic specificity of decreased serum cobalamin levels, demonstrating...
17.
Allen R, Stabler S, Savage D, Lindenbaum J
FASEB J . 1993 Nov; 7(14):1344-53. PMID: 7901104
Mammalian cells contain two Cbl-dependent enzymes, L-methylmalonyl-CoA mutase and methionine synthase. The former requires adenosyl-Cbl and catalyzes the conversion of L-methylmalonyl-CoA to succinyl-CoA. The latter requires CH3-Cbl and catalyzes the...
18.
Allen R, Stabler S, Lindenbaum J
Metabolism . 1993 Nov; 42(11):1448-60. PMID: 7694037
Homocysteine and 5-CH3-tetrahydrofolate (5-CH3-THF) are converted to methionine and THF by the CH3-cobalamin (CH3-Cbl)-dependent enzyme methionine synthase. Serum homocysteine levels are elevated in more than 95% of patients with Cbl...
19.
Joosten E, van den Berg A, Riezler R, Naurath H, Lindenbaum J, Stabler S, et al.
Am J Clin Nutr . 1993 Oct; 58(4):468-76. PMID: 8037789
Measurements of the serum concentrations of the metabolites homocysteine, cystathionine, methylmalonic acid, and 2-methylcitric acid, which accumulates when vitamin B-12-, folate-, and vitamin B-6-dependent enzymatic reactions are impaired, should provide...
20.
Allen R, Stabler S, Savage D, Lindenbaum J
Metabolism . 1993 Aug; 42(8):978-88. PMID: 8345822
Citrate synthase catalyzes the condensation of acetyl-coenzyme A (CoA) and oxaloacetic acid to form citric acid. The enzyme also catalyzes the condensation of propionyl-CoA and oxaloacetic acid with a maximal...