J L Christensen
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Explore the profile of J L Christensen including associated specialties, affiliations and a list of published articles.
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22
Citations
664
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Recent Articles
1.
Wagers A, Christensen J, Weissman I
Gene Ther
. 2002 May;
9(10):606-12.
PMID: 12032706
In the adult, tissue-specific stem cells are thought to be responsible for the replacement of differentiated cells within continuously regenerating tissues, such as the liver, skin, and blood system. In...
2.
Christensen J, Weissman I
Proc Natl Acad Sci U S A
. 2001 Nov;
98(25):14541-6.
PMID: 11724967
Clonogenic multipotent mouse hematopoietic stem cells (HSCs) and progenitor cells are contained within the c-kit(+) (K) lineage(-/lo) (L) Sca-1(+) (S) population of hematopoietic cells; long-term (LT) and short-term (ST) HSCs...
3.
Wright D, Cheshier S, Wagers A, Randall T, Christensen J, Weissman I
Blood
. 2001 Apr;
97(8):2278-85.
PMID: 11290588
Cytokine-mobilized peripheral blood hematopoietic stem cells (MPB HSC) are widely used for transplantation in the treatment of malignancies, but the mechanism of HSC mobilization is unclear. Although many HSC in...
4.
Neamati N, Turpin J, Winslow H, Christensen J, Williamson K, Orr A, et al.
J Med Chem
. 1999 Aug;
42(17):3334-41.
PMID: 10464020
A series of thiazolothiazepines were prepared and tested against purified human immunodeficiency virus type-1 integrase (HIV-1 IN) and viral replication. Structure-activity studies reveal that the compounds possessing the pentatomic moiety...
5.
Hong H, Neamati N, Winslow H, Christensen J, Orr A, Pommier Y, et al.
Antivir Chem Chemother
. 1998 Dec;
9(6):461-72.
PMID: 9865384
The rapid emergence of human immunodeficiency virus (HIV) strains resistant to available drugs implies that effective treatment modalities will require the use of a combination of drugs targeting different sites...
6.
Neamati N, Hong H, Owen J, Sunder S, Winslow H, Christensen J, et al.
J Med Chem
. 1998 Aug;
41(17):3202-9.
PMID: 9703465
In previous studies we identified N,N'-bis(salicylhydrazine) (1) as a lead compound against purified recombinant HIV-1 integrase. We have now expanded upon these earlier observations and tested 45 novel hydrazides. Among...
7.
Christensen J
Optom Vis Sci
. 1996 Jun;
73(6):428-34.
PMID: 8807656
In 1901, when optometry first achieved legal status, optometric education in the United States was inadequate. Two-week courses in refraction, correspondence courses, and 2 year apprenticeships were common. Over the...
8.
Walsh C, Matloubian M, Liu C, Ueda R, Kurahara C, Christensen J, et al.
Proc Natl Acad Sci U S A
. 1994 Nov;
91(23):10854-8.
PMID: 7526382
Mice lacking the perforin gene were generated by using targeted gene disruption in embryonal stem cells. When infected with lymphocytic choriomeningitis virus (LCMV), perforin-less (-/-) mice showed clear signs of...
9.
Buxbaum J, Christensen J, Ruefli A, Greengard P, Loring J
Biochem Biophys Res Commun
. 1993 Dec;
197(2):639-45.
PMID: 8267600
A major component of amyloid deposits found in Alzheimer disease and Down syndrome is the beta/A4 peptide, which is derived from the Alzheimer amyloid protein precursor (APP). Recent evidence indicates...
10.
Christensen J
J Am Optom Assoc
. 1992 Dec;
63(12):838-40.
PMID: 1287060
Change has affected physiological optics graduate programs' fulfillment of their original purpose of providing faculty for the schools and colleges of optometry. Relevant change has been divided into two categories:...