J K Lazdins
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Explore the profile of J K Lazdins including associated specialties, affiliations and a list of published articles.
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23
Citations
379
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Recent Articles
1.
Hobi R, Hubscher U, Neftel K, Alteri E, PONCIONI B, Walker M, et al.
Antivir Chem Chemother
. 2001 Aug;
12(2):109-18.
PMID: 11527042
Cephalosporins in aqueous solutions generate degradation products that inhibit in vitro HIV-1 replication in cell lines, as well as in primary cells (lymphocytes and macrophages). This effect is observed at...
2.
Horton J, Witt C, Ottesen E, Lazdins J, Addiss D, Awadzi K, et al.
Parasitology
. 2001 Jun;
121 Suppl:S147-60.
PMID: 11386686
This review of the safety of the co-administration regimens to be used in programmes to eliminate lymphatic filariasis (albendazole + ivermectin or albendazole + diethylcarbamazine [DEC]) is based on 17...
3.
Lazdins J, Mestan J, Goutte G, Walker M, Bold G, Capraro H, et al.
J Infect Dis
. 1997 May;
175(5):1063-70.
PMID: 9129067
Protein binding can impair the potency of human immunodeficiency virus (HIV) protease inhibitors. Therefore, the activity of a novel compound, CGP 61755, was studied in the absence or presence of...
4.
Lazdins J, Grell M, Walker M, Scheurich P, Pfizenmaier K
J Exp Med
. 1997 Jan;
185(1):81-90.
PMID: 8996244
Tumor necrosis factor (TNF) and lymphotoxin (LT) are highly pleiotropic cytokines that play a central role in regulating HIV-1 replication. These cytokines express their activities through two membrane receptors, TNFR60...
5.
Lazdins J, Bold G, Capraro H, Cozens R, Fassler A, Flesch G, et al.
Schweiz Med Wochenschr
. 1996 Oct;
126(43):1849-51.
PMID: 8916294
CGP 61755 is a novel hydroxyethylene derivative produced by a high yield 10 step chemical synthesis. It is highly specific for HIV-1 protease with an IC50 of 1 nM. The...
6.
Lazdins J, Klimkait T, Walker M, Alteri E, Cox D, Cerletti N, et al.
AIDS Res Hum Retroviruses
. 1992 Apr;
8(4):505-11.
PMID: 1599757
In vitro exposure of human blood monocyte-derived macrophages to T-cell tropic human immunodeficiency virus (HIV) isolates fails to establish a productive viral infection. Several studies have shown that such preferential...
7.
Lazdins J, Alteri E, Klimkait T, Walker M, Goutte G, PONCIONI B
Lancet
. 1991 Nov;
338(8778):1341-2.
PMID: 1682729
No abstract available.
8.
Lazdins J, Klimkait T, Walker M, Alteri E, Cox D, Cerletti N, et al.
J Immunol
. 1991 Aug;
147(4):1201-7.
PMID: 1869819
In vitro-differentiated monocytes can be infected with the monocytotropic isolate of HIV-1/ADA. The infection is characterized by formation of giant cells and production of virus that can be found in...
9.
Lazdins J, Klimkait T, Alteri E, Walker M, Cox D, Bilbe G, et al.
Res Virol
. 1991 Mar;
142(2-3):239-42.
PMID: 1896646
TGF-beta at physiological concentrations, when added to monocyte-derived macrophages following HIV1 infection, has an enhancing effect upon the rate of virus production. This effect is observed with the monocytotropic isolate...
10.
James S, Cook K, Lazdins J
J Immunol
. 1990 Oct;
145(8):2686-90.
PMID: 1698860
Human peripheral blood monocytes from normal donors were isolated by elutriation and differentiated by culture in the presence or absence of various immunomodulators. Cells were harvested between 0 and 24...