J H PIERCE
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Explore the profile of J H PIERCE including associated specialties, affiliations and a list of published articles.
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Articles
151
Citations
4081
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Recent Articles
11.
Hijazi M, Young P, Dougherty M, Bressette D, Cao T, PIERCE J, et al.
Int J Oncol
. 1998 Oct;
13(5):1061-7.
PMID: 9772300
Ligands of the EGF/Heregulin family control the growth of epithelial cells by binding to receptors of the erbB family. By searching a large database of cDNA sequences at Human Genome...
12.
Myers Jr M, Mendez R, Shi P, PIERCE J, Rhoads R, White M
J Biol Chem
. 1998 Oct;
273(41):26908-14.
PMID: 9756938
Activation of tyrosine kinases by numerous growth factor and cytokine receptors leads to tyrosine phosphorylation of the insulin receptor substrate (IRS)-proteins. Tyrosine-phosphorylated motifs on the IRS proteins bind to the...
13.
Pinkas-Kramarski R, Shelly M, Guarino B, Wang L, Lyass L, Alroy I, et al.
Mol Cell Biol
. 1998 Sep;
18(10):6090-101.
PMID: 9742126
The recently isolated second family of neuregulins, NRG2, shares its primary receptors, ErbB-3 and ErbB-4, and induction of mammary cell differentiation with NRG1 isoforms, suggesting functional redundancy of the two...
14.
Li W, Jiang Y, Zhang J, Soon L, Flechner L, Kapoor V, et al.
Mol Cell Biol
. 1998 Sep;
18(10):5888-98.
PMID: 9742106
To investigate the potential role of protein kinase C-delta (PKC-delta) in insulin-like growth factor I receptor (IGF-IR)-mediated cell transformation, an oncogenic gag-IGF-IR beta-fusion receptor lacking the entire extracellular domain, which...
15.
Tang C, Goldstein D, Payne J, Czubayko F, Alimandi M, Wang L, et al.
Cancer Res
. 1998 Aug;
58(15):3415-22.
PMID: 9699674
The epidermal growth factor-like receptor tyrosine kinase (ErbB) family is frequently overexpressed in a variety of human carcinomas, including breast cancer. To assist in characterizing the role of ErbB-4 in...
16.
Wang L, Kuo A, Alimandi M, Veri M, Lee C, Kapoor V, et al.
Proc Natl Acad Sci U S A
. 1998 Jun;
95(12):6809-14.
PMID: 9618494
Interleukin 3-dependent murine 32D cells do not detectably express members of the ErbB receptor family and do not proliferate in response to known ligands for these receptors. 32D transfectants were...
17.
Shelly M, Pinkas-Kramarski R, Guarino B, Waterman H, Wang L, Lyass L, et al.
J Biol Chem
. 1998 May;
273(17):10496-505.
PMID: 9553109
The ErbB signaling network consists of four transmembrane receptor tyrosine kinases and more than a dozen ligands sharing an epidermal growth factor (EGF) motif. The multiplicity of ErbB-specific ligands is...
18.
Yang D, Kuan C, Payne J, Kihara A, Murray A, Wang L, et al.
Clin Cancer Res
. 1998 May;
4(4):993-1004.
PMID: 9563895
Growth factor receptors provide unique opportunities for development of targeted anticancer therapy. Members of the type I receptor tyrosine kinase family, including epidermal growth factor (EGF) receptor (EGFR) and ErbB-2/neu,...
19.
Patel B, PIERCE J, LaRochelle W
Proc Natl Acad Sci U S A
. 1998 Feb;
95(1):172-7.
PMID: 9419348
Interleukin (IL)-4-mediated nuclear signaling by Stat6 has been implicated in lymphoid cell proliferation and the transcriptional activation of genes encoding major histocompatability complex (MHC) class II molecules and Fc receptors....
20.
Alimandi M, Wang L, Bottaro D, Lee C, Kuo A, Frankel M, et al.
EMBO J
. 1997 Oct;
16(18):5608-17.
PMID: 9312020
Interleukin-3 (IL-3)-dependent murine 32D cells do not detectably express epidermal growth factor receptors (EGFRs) and do not proliferate in response to EGF, heregulin (HRG) or other known EGF-like ligands. Here,...