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J H Morrissey

Explore the profile of J H Morrissey including associated specialties, affiliations and a list of published articles. Areas
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Articles 102
Citations 3237
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Recent Articles
1.
Muller M, Wang Y, Morrissey J, Tajkhorshid E
J Thromb Haemost . 2017 Aug; 15(10):2005-2016. PMID: 28782177
Summary: Background Factor X (FX) binds to cell membranes in a highly phospholipid-dependent manner and, in complex with tissue factor and factor VIIa (FVIIa), initiates the clotting cascade. Experimental information...
2.
Morrissey J, Smith S
J Thromb Haemost . 2015 Jul; 13 Suppl 1:S92-7. PMID: 26149055
Inorganic polyphosphate (polyP), a linear polymer of phosphates, is present in many infectious microorganisms and is secreted by mast cells and platelets. PolyP has recently been shown to accelerate blood...
3.
Travers R, Smith S, Morrissey J
Int J Lab Hematol . 2015 May; 37 Suppl 1:31-5. PMID: 25976958
While we have understood the basic outline of the enzymes and reactions that make up the traditional blood coagulation cascade for many years, recently our appreciation of the complexity of...
4.
Geng Y, Verhamme I, Smith S, Cheng Q, Sun M, Sheehan J, et al.
J Thromb Haemost . 2013 Oct; 11(11):2020-8. PMID: 24118982
Background: Conversion of factor XI (FXI) to FXIa is enhanced by polymers of inorganic phosphate (polyP). This process requires FXI to bind to polyP. Each FXIa subunit contains anion-binding sites...
5.
Puy C, Tucker E, Wong Z, Gailani D, Smith S, Choi S, et al.
J Thromb Haemost . 2013 May; 11(7):1341-52. PMID: 23659638
Background: Inorganic polyphosphates (polyP), which are secreted by activated platelets (short-chain polyP) and accumulate in some bacteria (long-chain polyP), support the contact activation of factor XII (FXII) and accelerate the...
6.
Morrissey J
J Thromb Haemost . 2012 Sep; 10(11):2313-4. PMID: 23006797
No abstract available.
7.
Mutch N, Waters E, Morrissey J
J Thromb Haemost . 2012 Aug; 10(10):2108-15. PMID: 22905925
Background: Upon contact with an appropriate surface, factor XII (FXII) undergoes autoactivation or cleavage by kallikrein. Zn(2+) is known to facilitate binding of FXII and the cofactor, high molecular weight...
8.
Morrissey J
Thromb Haemost . 2012 Jul; 108(2):206. PMID: 22782428
No abstract available.
9.
Morrissey J, Tajkhorshid E, Rienstra C
J Thromb Haemost . 2011 Jul; 9 Suppl 1:162-7. PMID: 21781251
Most of the steps in the blood clotting cascade require clotting proteins to bind to membrane surfaces with exposed phosphatidylserine. In spite of the importance of these protein-membrane interactions, we...
10.
Morrissey J
J Thromb Haemost . 2011 Jun; 9(8):1508-10. PMID: 21679295
No abstract available.