J H Fleisch
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Explore the profile of J H Fleisch including associated specialties, affiliations and a list of published articles.
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75
Citations
416
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Recent Articles
1.
Kuwabara K, Jyoyama H, Fleisch J, Hori Y
Inflamm Res
. 2003 Jan;
51(11):541-50.
PMID: 12540018
Objective And Design: To investigate the role of leukotriene B4 (LTB4) and prostaglandin E2 (PGE2) in the development and progression of antigen-induced arthritis (AIA) in guinea pigs and rats. Methods:...
2.
Asanuma F, Kuwabara K, Arimura A, Furue Y, Fleisch J, Hori Y
Inflamm Res
. 2001 May;
50(3):136-41.
PMID: 11339501
Objective And Design: LY29311 Na, 2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5-hydroxyphenoxy] propoxy] -phenoxy]-benzoic acid sodium salt, is a novel leukotriene B4 (LTB4) receptor antagonist. Its effects on guinea pig models of asthma were compared with...
3.
ONeill M, Hicks C, Ward M, Osborne D, Wishart G, Mathews K, et al.
Brain Res
. 2001 Jan;
888(1):138-149.
PMID: 11146060
In the present studies we have examined the effects of a new calcium channel blocker, LY393615 ((N-Butyl-[5,5-bis-(4-fluorophenyl)tetrahydrofuran-2-yl]methylamine hydrochloride, NCC1048) in a model of hypoxia-hypoglycaemia in vitro and in a gerbil...
4.
Kuwabara K, Yasui K, Jyoyama H, Maruyama T, Fleisch J, Hori Y
Eur J Pharmacol
. 2000 Aug;
402(3):275-85.
PMID: 10958895
The effects of the second-generation leukotriene B(4) receptor (LTB(4) receptor) antagonist, 2-[2-propyl-3-¿3-[2-ethyl-4-(4-fluorophenyl)-5-hydroxy-phenoxy]-propo xy¿phenoxy]benzoic acid sodium salt (LY293111Na), on leukotriene B(4)-induced leukocyte infiltration and interleukin-1-accelerated collagen-induced arthritis in mice were studied....
5.
ONeill M, Murray T, McCarty D, Hicks C, Dell C, Patrick K, et al.
Brain Res
. 2000 Jul;
871(2):234-44.
PMID: 10899290
In the present studies, we have evaluated the effects of N-[4-(2-¿[(3-Chlorophenyl)methyl]amino¿ethyl)phenyl]-2-thiophenecarbo ximidamide dihydrochloride (ARL 17477) on recombinant human neuronal NOS (nNOS) and endothelial NOS (eNOS). We then carried out pharmacokinetic...
6.
Snyder D, Bach N, DILLARD R, Draheim S, Carlson D, Fox N, et al.
J Pharmacol Exp Ther
. 1999 Feb;
288(3):1117-24.
PMID: 10027849
LY315920 is a potent, selective inhibitor of recombinant human, group IIA, nonpancreatic secretory PLA2 (sPLA2). In a chromogenic isolated enzyme assay, LY315920 inhibited sPLA2 activity with an IC50 of 9...
7.
Jackson W, Froelich L, Boyd R, Schrementi J, Saussy Jr D, Schultz R, et al.
J Pharmacol Exp Ther
. 1998 Dec;
288(1):286-94.
PMID: 9862783
The in vitro actions were investigated of LY293111, a potent and selective leukotriene B4 (LTB4) receptor antagonist, on human neutrophils, human blood fractions, guinea pig lung membranes, and guinea pig...
8.
Sofia M, Floreancig P, Bach N, Baker S, Nelson K, Sawyer J, et al.
Adv Exp Med Biol
. 1997 Jan;
400A:381-6.
PMID: 9547580
No abstract available.
9.
Fleisch J, Armstrong C, Roman C, Mihelich E, Spaethe S, Jackson W, et al.
J Pharmacol Exp Ther
. 1996 Jul;
278(1):252-7.
PMID: 8764358
The primary objective of this study was to develop a functional assay that could provide rapid and reliable information on some pharmacologic characteristics of a novel inhibitor of human secretory...
10.