J F Mouscadet
Overview
Explore the profile of J F Mouscadet including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
32
Citations
388
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Agapkina I, Tashlitskii V, Deprez E, Brochon J, Shugalii A, Mouscadet J, et al.
Mol Biol (Mosk)
. 2004 Nov;
38(5):848-57.
PMID: 15554187
Human immunodeficiency virus type 1 integrase is one of three viral enzymes, and it realizes a key process of the viral replication cycle, i.e. viral DNA integration into infected cell...
2.
Pinskaya M, Volkov M, Romanova E, Volkov E, Mouscadet J, Gottikh M
Dokl Biochem Biophys
. 2004 May;
394:35-8.
PMID: 15116565
No abstract available.
3.
Dupont R, Jeanson L, Mouscadet J, Cotelle P
Bioorg Med Chem Lett
. 2001 Nov;
11(24):3175-8.
PMID: 11720868
Fourteen catechol and bis-catechol derivatives have been synthesised and tested for their HIV-1 inhibitory activities. The six more active molecules have been tested for their antiviral activity and cytotoxicity. We...
4.
Maroun R, Gayet S, Benleulmi M, Porumb H, Zargarian L, Merad H, et al.
Biochemistry
. 2001 Nov;
40(46):13840-8.
PMID: 11705373
Integration of HIV-1 genome into host cell chromosome is mediated by viral integrase (IN). The IN catalytic core (CC, IN(50-212)) dimerizes through mutual interactions of its alpha1 and alpha5 helices....
5.
Brodin P, Pinskaya M, Parsch U, Bischerour J, Leh H, Romanova E, et al.
Nucleosides Nucleotides Nucleic Acids
. 2001 Sep;
20(4-7):481-6.
PMID: 11563063
Integration of the proviral DNA into the genome of infected cells is a key step of HIV-1 replication. Integration is catalyzed by the viral enzyme integrase (IN). 6-oxocytidine-containing oligonucleotides were...
6.
Deprez E, Tauc P, Leh H, Mouscadet J, Auclair C, Hawkins M, et al.
Proc Natl Acad Sci U S A
. 2001 Aug;
98(18):10090-5.
PMID: 11504911
Self-assembly of HIV-1 integrase (IN) in solution has been studied previously by time-resolved fluorescence, using tryptophan anisotropy decay. This approach provides information on the size of macromolecules via the determination...
7.
Laboulais C, Deprez E, Leh H, Mouscadet J, Brochon J, Le Bret M
Biophys J
. 2001 Jun;
81(1):473-89.
PMID: 11423430
Two molecular dynamics simulations have been carried out on the HIV-1 integrase catalytic core starting from fully determined crystal structures. During the first one, performed in the absence of divalent...
8.
dAngelo J, Mouscadet J, Desmaele D, Zouhiri F, Leh H
Pathol Biol (Paris)
. 2001 May;
49(3):237-46.
PMID: 11367559
HIV-1 is the aetiological agent of AIDS. Present treatment of AIDS uses a combination therapy with reverse transcriptase and protease inhibitors. Recently, the integrase (IN), the third enzyme of HIV-1...
9.
Pinskaia M, Brodin P, Romanova E, Volkov E, Mouscadet J, Gottikh M
Mol Biol (Mosk)
. 2001 Feb;
34(6):1039-45.
PMID: 11186003
No abstract available.
10.
Ouali M, Laboulais C, Leh H, Gill D, Xhuvani E, Zouhiri F, et al.
Acta Biochim Pol
. 2000 Aug;
47(1):11-22.
PMID: 10961674
8-Hydroxy-2-[2-(3-hydroxy-4-methoxyphenyl)ethenyl]-7-quinoline carboxylic acid and 8-hydroxy-2-[2-(3-methoxy-4-hydroxyphenyl)ethenyl]-7-quinoline carboxylic acid inhibit the processing and strand transfer reactions catalyzed by HIV-1 integrase with an IC50 of 2 microM. Some of their spectral properties are...