J F Gregory 3rd
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Explore the profile of J F Gregory 3rd including associated specialties, affiliations and a list of published articles.
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82
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670
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Recent Articles
1.
Ding Y, Pedersen E, Johansson S, Gregory 3rd J, Ueland P, Svingen G, et al.
Nutr Metab Cardiovasc Dis
. 2016 Jan;
26(6):495-501.
PMID: 26803590
Background: Methylenetetrahydrofolate dehydrogenase (MTHFD1) catalyzes three sequential reactions that metabolize derivatives of tetrahydrofolate (THF) in folate-dependent one-carbon metabolism. Impaired MTHFD1 flux has been linked to disturbed lipid metabolism and oxidative...
2.
Cuskelly G, Stacpoole P, Williamson J, Baumgartner T, Gregory 3rd J
Am J Physiol Endocrinol Metab
. 2001 Nov;
281(6):E1182-90.
PMID: 11701432
Folate and vitamin B(6) act in generating methyl groups for homocysteine remethylation, but the kinetic effects of folate or vitamin B(6) deficiency are not known. We used an intravenous primed,...
3.
Gregory 3rd J, Caudill M, Opalko F, Bailey L
J Nutr
. 2001 Jul;
131(7):1928-37.
PMID: 11435509
To investigate the effects of pregnancy on folate metabolism, we conducted an 84-d study in second-trimester (gestational wk 14-25) pregnant women (n = 6) and nonpregnant controls (n = 6)...
4.
Gregory 3rd J
J Nutr
. 2001 Apr;
131(4 Suppl):1376S-82S.
PMID: 11285357
Folate nutritional status depends on intake from food and supplements as well as on the bioavailability of the various ingested forms of this vitamin. Although many advances in the understanding...
5.
Gregory 3rd J, SWENDSEID M, Jacob R
J Nutr
. 2000 Dec;
130(12):2949-52.
PMID: 11110852
Folate turnover involves urinary excretion, fecal excretion, and catabolism that involves cleavage of the C9-N10 bond to yield pterins and para-aminobenzoylglutamate (pABG). Little is known about the relationship between the...
6.
Gregory 3rd J, Cuskelly G, Shane B, Toth J, Baumgartner T, Stacpoole P
Am J Clin Nutr
. 2000 Dec;
72(6):1535-41.
PMID: 11101483
Background: One-carbon metabolism involves both mitochondrial and cytosolic forms of folate-dependent enzymes in mammalian cells, but few in vivo data exist to characterize the biochemical processes involved. Objective: We conducted...
7.
Boddie A, Dedlow E, Nackashi J, Opalko F, Kauwell G, Gregory 3rd J, et al.
Am J Clin Nutr
. 2000 Jun;
72(1):154-8.
PMID: 10871574
Background: The risk of neural tube defects (NTDs) is significantly reduced by supplemental folic acid. NTD risk may be associated with impaired absorption of polyglutamyl folate, the primary form of...
8.
Martinez M, Cuskelly G, Williamson J, Toth J, Gregory 3rd J
J Nutr
. 2000 May;
130(5):1115-23.
PMID: 10801907
Vitamin B-6 deficiency causes mild elevation in plasma homocysteine, but the mechanism has not been clearly established. Serine is a substrate in one-carbon metabolism and in the transsulfuration pathway of...
9.
Bailey L, Gregory 3rd J
J Nutr
. 1999 May;
129(5):919-22.
PMID: 10222379
A common genetic polymorphism results from a C-->T substitution in the gene encoding methylenetetrahydrofolate reductase (MTHFR), the enzyme that produces 5-methyltetrahydrofolate (5-methyl-THF) required for the conversion of homocysteine to methionine....
10.
Bailey L, Gregory 3rd J
J Nutr
. 1999 Apr;
129(4):779-82.
PMID: 10203550
Folate functions in multiple coenzyme forms in acceptance, redox processing and transfer of one-carbon units, including nucleotides and certain amino acids. Folate-requiring metabolic processes are influenced by folate intake, intake...