J E Pessin
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Explore the profile of J E Pessin including associated specialties, affiliations and a list of published articles.
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Articles
148
Citations
4108
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Recent Articles
11.
Kanzaki M, Pessin J
J Biol Chem
. 2001 Sep;
276(45):42436-44.
PMID: 11546823
Rhodamine-labeled phalloidin staining of morphologically differentiated 3T3L1 adipocytes demonstrated that F-actin predominantly exists juxtaposed to and lining the inner face of the plasma membrane (cortical actin) with a smaller amount...
12.
Watson R, Shigematsu S, Chiang S, Mora S, Kanzaki M, Macara I, et al.
J Cell Biol
. 2001 Aug;
154(4):829-40.
PMID: 11502760
Recent studies indicate that insulin stimulation of glucose transporter (GLUT)4 translocation requires at least two distinct insulin receptor-mediated signals: one leading to the activation of phosphatidylinositol 3 (PI-3) kinase and...
13.
Watson R, Pessin J
Am J Physiol Cell Physiol
. 2001 Jun;
281(1):C215-23.
PMID: 11401844
Insulin recruits glucose transporter 4 (GLUT-4) vesicles from intracellular stores to the plasma membrane in muscle and adipose tissue by specific interactions between the vesicle membrane-soluble N-ethylmaleimide-sensitive factor attachment protein...
14.
Yang C, Coker K, Kim J, Mora S, Thurmond D, Davis A, et al.
J Clin Invest
. 2001 May;
107(10):1311-8.
PMID: 11375421
To investigate the physiological function of syntaxin 4 in the regulation of GLUT4 vesicle trafficking, we used homologous recombination to generate syntaxin 4-knockout mice. Homozygotic disruption of the syntaxin 4...
15.
Mora S, Yang C, Ryder J, Boeglin D, Pessin J
Endocrinology
. 2001 Apr;
142(5):1999-2004.
PMID: 11316766
Previously we have demonstrated that striated muscle GLUT4 gene expression decreased following streptozotocin-induced diabetes due to a loss of MEF2A transcription factor expression without any significant effect on the MEF2D...
16.
Chiang S, BAUMANN C, Kanzaki M, Thurmond D, Watson R, Neudauer C, et al.
Nature
. 2001 Apr;
410(6831):944-8.
PMID: 11309621
The stimulation of glucose uptake by insulin in muscle and adipose tissue requires translocation of the GLUT4 glucose transporter protein from intracellular storage sites to the cell surface. Although the...
17.
Shigematsu S, Miller S, Pessin J
J Biol Chem
. 2001 Mar;
276(18):15292-7.
PMID: 11278545
Various studies have demonstrated that the platelet-derived growth factor (PDGF) receptor in adipocytes can activate PI 3-kinase activity without affecting insulin-responsive glucose transporter (GLUT4) translocation. To investigate this phenomenon of...
18.
Yang C, Mora S, Ryder J, Coker K, Hansen P, Allen L, et al.
Mol Cell Biol
. 2001 Mar;
21(5):1573-80.
PMID: 11238894
To investigate the physiological function of the VAMP3 vesicle SNARE (v-SNARE) isoform in the regulation of GLUT4 vesicle trafficking, we generated homozygotic VAMP3 null mice by targeted gene disruption. The...
19.
Watson R, Pessin J
Recent Prog Horm Res
. 2001 Mar;
56:175-93.
PMID: 11237212
Glucose is cleared from the bloodstream by a family of facilitative transporters (GLUTs), which catalyze the transport of glucose down its concentration gradient and into cells of target tissues, primarily...
20.
Khan A, Thurmond D, Yang C, Ceresa B, Sigmund C, Pessin J
J Biol Chem
. 2000 Oct;
276(6):4063-9.
PMID: 11054418
To examine the intracellular trafficking and translocation of GLUT4 in skeletal muscle, we have generated transgenic mouse lines that specifically express a GLUT4-EGFP (enhanced green fluorescent protein) fusion protein under...