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J E Manning

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Articles 79
Citations 1276
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Recent Articles
1.
Manning J, Katz L, Pearce L, Batson D, McCurdy S, Gawryl M, et al.
Crit Care Med . 2001 Nov; 29(11):2067-74. PMID: 11700396
Objective: The prospects for resuscitation after blunt traumatic cardiac arrest are dismal. Selective aortic arch perfusion (SAAP) with a hemoglobin-based oxygen carrier (HBOC-201) offers a potentially effective therapy. This study...
2.
Yoshikawa H, Matsubara K, Qian G, Jackson P, Groopman J, Manning J, et al.
Nat Genet . 2001 Apr; 28(1):29-35. PMID: 11326271
Hepatocellular carcinoma (HCC) is a major cause of cancer death, but the molecular mechanism for its development beyond its initiation has not been well characterized. Suppressor of cytokine signaling (SOCS-1;...
3.
de Diego J, Katz J, Marshall P, Gutierrez B, Manning J, NUSSENZWEIG V, et al.
Biochemistry . 2001 Feb; 40(4):1053-62. PMID: 11170428
Here, we document for the first time the presence of the 26S proteasome and the ubiquitin pathway in a protozoan parasite that is in an early branch in the eukaryotic...
4.
Manning J, Katz L
Crit Care Clin . 2000 Nov; 16(4):659-79. PMID: 11070810
The future of cardiopulmonary resuscitation lies in new technologies for monitoring and generating vital organ perfusion during cardiac arrest and the post-resuscitation phase and in pharmacologic agents that will enhance...
5.
Manning J, Katz L, Brownstein M, Pearce L, Gawryl M, Baker C
Shock . 2000 Feb; 13(2):152-9. PMID: 10670846
In the setting of rapidly exsanguinating hemorrhage, resuscitation with intravenous (i.v.) crystalloid solution may not sustain survival before availability of allogenic blood transfusion and surgery. This study tested the hypothesis...
6.
Wrightsman R, Manning J
Vaccine . 2000 Jan; 18(14):1419-27. PMID: 10618540
Successful vaccination of mice against an otherwise lethal challenge with the Peru strain of Trypanosoma cruzi necessitates the induction of a strong cell mediated immune response. Previously, immunization of mice...
7.
Quanquin N, Galaviz C, Fouts D, Wrightsman R, Manning J
Infect Immun . 1999 Aug; 67(9):4603-12. PMID: 10456906
The gene family encoding a trypomastigote-specific protein restricted to the part of the flagellum in contact with the cell body of the trypomastigote form of Trypanosoma cruzi has been isolated,...
8.
Giordano R, Fouts D, Tewari D, Colli W, Manning J, Alves M
J Biol Chem . 1999 Jan; 274(6):3461-8. PMID: 9920891
Trypomastigotes of Trypanosoma cruzi express a set of surface glycoproteins known, collectively, as Tc-85. A monoclonal antibody to these proteins, named H1A10, inhibits (50-90%) in vitro parasite interiorization into host...
9.
Fouts D, Stryker G, Gorski K, Miller M, Nguyen T, Wrightsman R, et al.
J Biol Chem . 1998 Aug; 273(34):21846-55. PMID: 9705323
The major structural proteins present in the paraflagellar rod of Trypanosoma cruzi migrate on SDS-polyacrylamide gels as two distinct electrophoretic bands. The gene encoding a protein present in the faster...
10.
Manning J, Goldin J, Shpiner R, Aberle D
Clin Radiol . 1998 May; 53(4):302-9. PMID: 9585049
No abstract available.