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J E Cleaver

Explore the profile of J E Cleaver including associated specialties, affiliations and a list of published articles. Areas
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Articles 252
Citations 2843
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Recent Articles
11.
Limoli C, Laposa R, Cleaver J
Mutat Res . 2002 Dec; 510(1-2):121-9. PMID: 12459448
Ultraviolet (UV) irradiation produces DNA photoproducts that are blocks to DNA replication by normal replicative polymerases. A specialized, damage-specific, distributive polymerase, Pol H or Pol h, that is the product...
12.
Cleaver J
Environ Mol Mutagen . 2001 Dec; 38(2-3):122-31. PMID: 11746745
Richard B. Setlow inspired the field of DNA repair. His demonstration that photoproducts could be quantified within cells and their excision examined experimentally pioneered the identification of nucleotide excision repair....
13.
Laposa R, Cleaver J
Proc Natl Acad Sci U S A . 2001 Nov; 98(23):12860-2. PMID: 11698674
No abstract available.
14.
Thakur M, Wernick M, Collins C, Limoli C, Crowley E, Cleaver J
Genes Chromosomes Cancer . 2001 Oct; 32(3):222-35. PMID: 11579462
Polymerase eta (pol eta) is a low-fidelity DNA polymerase that is the product of the gene, POLH, associated with the human XP variant disorder in which there is an extremely...
15.
Cleaver J
Trends Biochem Sci . 2001 Jun; 26(6):398-401. PMID: 11406414
No abstract available.
16.
Cleaver J, Karplus K, Kashani-Sabet M, Limoli C
Mutat Res . 2001 May; 485(1):23-36. PMID: 11341991
The first half of the 20th century has seen an enormous growth in our knowledge of DNA repair, in no small part due to the work of Dirk Bootsma, Philip...
17.
Limoli C, Giedzinski E, Morgan W, Cleaver J
Proc Natl Acad Sci U S A . 2000 Jun; 97(14):7939-46. PMID: 10859352
The xeroderma pigmentosum variant (XPV) is a genetic disease involving high levels of solar-induced cancer that has normal excision repair but shows defective DNA replication after UV irradiation because of...
18.
Savarirayan R, Gardner R, Sinclair R, McDowell M, Cleaver J
J Med Genet . 2000 May; 37(4):312-4. PMID: 10819642
No abstract available.
19.
Cleaver J
J Dermatol Sci . 2000 Mar; 23(1):1-11. PMID: 10699759
The human disease xeroderma pigmentosum (XP) involves DNA repair and replication deficiencies that predispose homozygous individuals to a 1000-fold increase in nonmelanoma and melanoma skin cancers. Two major forms of...
20.
Cleaver J, Thompson L, Richardson A, States J
Hum Mutat . 1999 Aug; 14(1):9-22. PMID: 10447254
The human diseases xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy are caused by mutations in a set of interacting gene products, which carry out the process of nucleotide excision repair. The...