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J D Pearson

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Articles 263
Citations 5487
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Recent Articles
11.
Martin A, Carides A, Pearson J, Horgan K, Elmer M, Schmidt C, et al.
Eur J Cancer . 2003 Jun; 39(10):1395-401. PMID: 12826042
Little information exists on the functional impact of effective antiemetic protection. In the present study, the Functional Living Index-Emesis (FLIE), was used to assess patient-reported impact of chemotherapy-induced nausea and...
12.
Polascik T, Pearson J, Partin A, Polascik D
Prostate Cancer Prostatic Dis . 2002 Dec; 1(6):301-306. PMID: 12496871
To benefit from definitive local therapy, men with clinically localized prostate cancer should have organ-confined disease. We discuss the use of multivariate analysis using serum PSA, biopsy Gleason score and...
13.
Partin A, Mangold L, Lamm D, Walsh P, Epstein J, Pearson J
Urology . 2001 Dec; 58(6):843-8. PMID: 11744442
Objectives: We previously presented nomograms combining preoperative serum prostate-specific antigen (PSA), clinical (TNM) stage, and biopsy Gleason score to provide the likelihood of various final pathologic stages at radical retropubic...
14.
Leung K, Wait R, Welson S, Yan J, Abraham D, Black C, et al.
Proteomics . 2001 Oct; 1(6):787-94. PMID: 11677786
We report the first protein map of human adult lung MRC-5 fibroblasts using isoelectric focusing-immobilized pH gradient-based two-dimensional polyacrylamide gel electrophoresis. MRC-5 is an immortalised cell line used in a...
15.
Wilcox S, Cavey G, Pearson J
Antimicrob Agents Chemother . 2001 Oct; 45(11):3046-55. PMID: 11600354
Mutations in several ribosomal proteins are known to be related to antibiotic resistance. For several strains of Escherichia coli, the mutated protein is known but the amino acid actually altered...
16.
Houliston R, Pearson J, Wheeler-Jones C
Am J Physiol Cell Physiol . 2001 Sep; 281(4):C1266-76. PMID: 11546664
We have examined the mechanisms regulating prostacyclin (PGI(2)) synthesis after acute exposure of human umbilical vein endothelial cells (HUVEC) to interleukin-1 alpha (IL-1 alpha). IL-1 alpha evoked an early (30...
17.
Aguayo C, Flores C, Parodi J, Rojas R, Mann G, Pearson J, et al.
J Physiol . 2001 Jul; 534(Pt 1):243-54. PMID: 11433005
1. Adenosine transport was measured in human cultured umbilical artery smooth muscle cells, isolated from non-diabetic or gestational diabetic pregnancies, under basal conditions and after pretreatment in vitro with insulin....
18.
Amos C, Romero I, Schultze C, Rousell J, Pearson J, Greenwood J, et al.
Arterioscler Thromb Vasc Biol . 2001 May; 21(5):810-6. PMID: 11348879
Intercellular adhesion molecule (ICAM)-1 plays a vital role in the process of leukocyte transmigration through endothelial cell (EC) barriers and has been shown to mediate signal transduction events in ECs...
19.
Shi-Wen X, Denton C, Dashwood M, Holmes A, Bou-Gharios G, Pearson J, et al.
J Invest Dermatol . 2001 Mar; 116(3):417-25. PMID: 11231316
This study examines endothelin-induced modulation of extracellular matrix synthesis and remodeling by fibroblasts, and its potential role in the pathogenesis of systemic sclerosis (scleroderma). Endothelin-1 promoted fibroblast synthesis of collagen...
20.
Parra M, Lees C, Mann G, Pearson J, Nicolaides K
Am J Obstet Gynecol . 2001 Mar; 184(3):497-502. PMID: 11228509
Objective: Preeclampsia and fetal growth restriction are associated with poor placental perfusion, which may be accompanied by a compensatory release of vasoactive substances in the fetoplacental circuit. This study examines...