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J D Marth

Explore the profile of J D Marth including associated specialties, affiliations and a list of published articles. Areas
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Articles 52
Citations 4140
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Recent Articles
1.
Wang Y, Tan J, Sutton-Smith M, Ditto D, Panico M, Campbell R, et al.
Glycobiology . 2002 Jan; 11(12):1051-70. PMID: 11805078
The congenital disorders of glycosylation (CDGs) are recent additions to the repertoire of inherited human genetic diseases. Frequency of CDGs is unknown since most cases are believed to be misdiagnosed...
2.
Moody A, Chui D, Reche P, Priatel J, Marth J, Reinherz E
Cell . 2001 Nov; 107(4):501-12. PMID: 11719190
The functional consequences of glycan structural changes associated with cellular differentiation are ill defined. Herein, we investigate the role of glycan adducts to the O-glycosylated polypeptide stalk tethering the CD8alphabeta...
3.
Sperandio M, Forlow S, Thatte J, Ellies L, Marth J, Ley K
J Immunol . 2001 Aug; 167(4):2268-74. PMID: 11490014
L-selectin is a calcium-dependent lectin on leukocytes mediating leukocyte rolling in high endothelial venules and inflamed microvessels. Many selectin ligands require modification of glycoproteins by leukocyte core2 beta1,6-N-acetylglucosaminyltransferase (Core2GlcNAcT-I). To...
4.
Yeh J, Hiraoka N, Petryniak B, Nakayama J, Ellies L, Rabuka D, et al.
Cell . 2001 Jul; 105(7):957-69. PMID: 11439191
L-selectin mediates lymphocyte homing by facilitating lymphocyte adhesion to addressins expressed in the high endothelial venules (HEV) of secondary lymphoid organs. Peripheral node addressin recognized by the MECA-79 antibody is...
5.
Sperandio M, Thatte A, Foy D, Ellies L, Marth J, Ley K
Blood . 2001 Jun; 97(12):3812-9. PMID: 11389021
Leukocyte capture and rolling are mediated by selectins expressed on leukocytes (L-selectin) and the vascular endothelium (P- and E-selectin). To investigate the role of core 2 beta1-6-N-glucosaminyltransferase (C2GlcNAcT-I) for synthesis...
6.
Snapp K, Heitzig C, Ellies L, Marth J, Kansas G
Blood . 2001 Jun; 97(12):3806-11. PMID: 11389020
Selectins are carbohydrate-binding adhesion molecules that play important roles in control of leukocyte traffic. Glycosyltransferases involved in selectin ligand biosynthesis include the alpha1,3-fucosyltransferases FucT-VII and FucT-IV, one or more sialyltransferases,...
7.
Zhu Y, Romero M, Ghosh P, Ye Z, Charnay P, Rushing E, et al.
Genes Dev . 2001 Apr; 15(7):859-76. PMID: 11297510
Neurofibromatosis type 1 (NF1) is a prevalent genetic disorder that affects growth properties of neural-crest-derived cell populations. In addition, approximately one-half of NF1 patients exhibit learning disabilities. To characterize NF1...
8.
DeFalco J, Tomishima M, Liu H, Zhao C, Cai X, Marth J, et al.
Science . 2001 Apr; 291(5513):2608-13. PMID: 11283374
We report the development of a pseudorabies virus that can be used for retrograde tracing from selected neurons. This virus encodes a green fluorescent protein marker and replicates only in...
9.
Priatel J, Chui D, Hiraoka N, Simmons C, Richardson K, Page D, et al.
Immunity . 2001 Feb; 12(3):273-83. PMID: 10755614
T lymphocyte activation evokes distinct changes in cell surface O-glycans. CD8+ T cells undergo an elimination of sialic acid on core 1 O-glycans and an induction of core 2 O-glycans...
10.
Marszalek J, Liu X, Roberts E, Chui D, Marth J, Williams D, et al.
Cell . 2000 Aug; 102(2):175-87. PMID: 10943838
To test whether kinesin-II is important for transport in the mammalian photoreceptor cilium, and to identify its potential cargoes, we used Cre-loxP mutagenesis to remove the kinesin-II subunit, KIF3A, specifically...