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J Cortijo

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Articles 115
Citations 820
Followers 0
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Recent Articles
1.
Aguilar-Serra J, Gimeno-Ballester V, Pastor-Clerigues A, Milara J, Trigo-Vicente C, Cortijo J
Expert Rev Pharmacoecon Outcomes Res . 2021 Oct; 22(4):637-646. PMID: 34602008
Aim: To evaluate the cost-effectiveness of first-line treatments, such as erlotinib, gefitinib, afatinib, dacomitinib, and osimertinib, for patients diagnosed with stage IIIB/IV NSCLC harboring EGFR mutations. Materials & Methods: A...
2.
Ortiz J, Milara J, Lluch J, de Diego A, Sanz C, Cortijo J
Allergy . 2012 Nov; 68(1):64-73. PMID: 23121078
Background: Several clinical studies have shown that smoking in asthmatics and chronic obstructive pulmonary disease patients is closely associated with corticosteroid refractoriness. In this work, we have analyzed glucocorticoid insensitivity...
3.
Herraiz S, Pellicer B, Serra V, Cauli O, Cortijo J, Felipo V, et al.
BJOG . 2012 Jul; 119(11):1394-402. PMID: 22827567
Objective: To evaluate perinatal outcome after sildenafil citrate (SC) administration at the onset of pregnancy in a rat pre-eclampsia model. Design: In vivo animal experimental study. Setting: Fundación IVI-Instituto Universitario...
4.
Milara J, Armengot M, Banuls P, Tenor H, Beume R, Artigues E, et al.
Br J Pharmacol . 2012 Mar; 166(8):2243-62. PMID: 22385203
Background And Purpose: Mucociliary malfunction occurs in chronic obstructive pulmonary disease (COPD) and compromised functions of ciliated bronchial epithelial cells may contribute to this. Cigarette smoke, a major risk factor...
5.
Milara J, Gabarda E, Juan G, Ortiz J, Guijarro R, Martorell M, et al.
Eur Respir J . 2011 Aug; 39(4):927-38. PMID: 21828025
The endothelin (ET) system contributes to lung vascular tension and remodelling in smokers and chronic obstructive pulmonary disease (COPD) patients. This study examined the effect of cigarette smoke (CS) on...
6.
Milara J, Navarro A, Almudever P, Lluch J, Morcillo E, Cortijo J
Clin Exp Allergy . 2011 Mar; 41(4):535-46. PMID: 21395877
Background: Oxidative stress is present in airway diseases such as severe asthma or Chronic Obstructive Pulmonary Disease and contributes to the low response to glucocorticoids through the down-regulation of histone...
7.
Pellicer B, Herraiz S, Cauli O, Rodrigo R, Asensi M, Cortijo J, et al.
BJOG . 2011 Jan; 118(5):615-23. PMID: 21244618
Objective: To determine the effects of chronic administration of sildenafil citrate on healthy pregnant rats. Design: In vivo animal experimental study. Setting: Fundación IVI-Instituto Universitario IVI, Valencia, Spain. Sample: Pregnant...
8.
Milara J, Ortiz J, Juan G, Guijarro R, Almudever P, Martorell M, et al.
Br J Pharmacol . 2010 Aug; 161(7):1599-615. PMID: 20698855
Background And Purpose: Pulmonary arteries from smokers and chronic obstructive pulmonary disease patients show abnormal endothelium-dependent vascular reactivity. We studied the effect of cigarette smoke extract (CSE) on endothelin receptor...
9.
Cortijo J, Mata M, Milara J, Donet E, Gavalda A, Miralpeix M, et al.
Eur Respir J . 2010 Jun; 37(2):244-54. PMID: 20525722
Mucus hypersecretion and mucin MUC5AC overexpression are pathological features of chronic obstructive pulmonary disease (COPD). This study examines the inhibitory effect of aclidinium, a new long-acting muscarinic antagonist, on MUC5AC...
10.
Alfon J, Ardanaz N, Gil-Torregrosa B, Fernandez A, Balsa D, Carceller E, et al.
Inflamm Res . 2009 Dec; 59 Suppl 2:S199-200. PMID: 20020315
No abstract available.