J C POWERS
Overview
Explore the profile of J C POWERS including associated specialties, affiliations and a list of published articles.
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Articles
175
Citations
1848
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0
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Recent Articles
1.
Gorrini M, Lupi A, Viglio S, Pamparana F, Cetta G, Iadarola P, et al.
Am J Respir Cell Mol Biol
. 2001 Nov;
25(4):492-9.
PMID: 11694455
Fourteen-member-ring macrolides are antibiotics with a variety of anti-inflammatory activities, and have repeatedly been reported to reduce mucus hypersecretion in conditions such as cystic fibrosis and bronchiectasis. Their structure is...
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3.
POWERS J, Kam C, Ricketts K, Casillas R
J Appl Toxicol
. 2001 Jun;
20 Suppl 1:S177-82.
PMID: 11428632
Tissue homogenates from mouse ear skin exposed to sulfur mustard (HD, which is a military designation and probably originated from a World War I slang term 'Hun Stuff') were assayed...
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Korver G, Kam C, POWERS J, Hudig D
Int Immunopharmacol
. 2001 May;
1(1):21-32.
PMID: 11367515
In granules of hematopoetic cells, dipeptidyl peptidase I (DPPI) processes inactive proenzymes into active enzymes, e.g., lymphocyte progranzyme A. Our goal was to develop irreversible inhibitors of intracellular DPPI. First,...
6.
Applegate R, Rankin K, POWERS J, Little W
Catheter Cardiovasc Interv
. 2001 May;
53(1):85-93.
PMID: 11329225
Abnormalities of diastolic function are increasingly recognized as important components of the abnormal physiology in many patients with heart failure. In order to better understand the role of abnormalities of...
7.
Gandhi S, POWERS J, NOMEIR A, Fowle K, Kitzman D, Rankin K, et al.
N Engl J Med
. 2001 Jan;
344(1):17-22.
PMID: 11136955
Background: Patients with acute pulmonary edema often have marked hypertension but, after reduction of the blood pressure, have a normal left ventricular ejection fraction (> or =0.50). However, the pulmonary...
8.
Morty R, Troeberg L, POWERS J, Ono S, Coetzer T
Biochem Pharmacol
. 2000 Oct;
60(10):1497-504.
PMID: 11020452
Two groups of irreversible serine peptidase inhibitors, peptidyl chloromethyl ketones and peptidyl phosphonate diphenyl esters, were examined for antitrypanosomal activity against the bloodstream form of Trypanosoma brucei brucei. Both peptidyl...
9.
Harriman J, Chu D, POWERS J, Schnellmann R
J Pharmacol Exp Ther
. 2000 Aug;
294(3):1083-7.
PMID: 10945863
Inhibitors of calpains, calcium-activated neutral proteases, protect against cell death produced by anoxia and a variety of toxicants both in vitro and in vivo. The problems with known calpain inhibitors...
10.
Kam C, Hudig D, POWERS J
Biochim Biophys Acta
. 2000 Mar;
1477(1-2):307-23.
PMID: 10708866
Natural killer (NK) and cytotoxic T-lymphocytes (CTLs) kill cells within an organism to defend it against viral infections and the growth of tumors. One mechanism of killing involves exocytosis of...