J C Metcalfe
Overview
Explore the profile of J C Metcalfe including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
163
Citations
2973
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Kirschenlohr H, Metcalfe J, Grainger D
Methods Mol Med
. 2011 Mar;
2:319-34.
PMID: 21359751
Abnormal proliferation of human vascular smooth muscle cells (hVSMCs) is a central event in the development of atherosclerosis (1-3) As a result, there is considerable interest in the establishment of...
2.
Griggs J, Metcalfe J, Hesketh R
Lancet Oncol
. 2002 Mar;
2(2):82-7.
PMID: 11905799
The requirement for neovascularisation to permit the development of solid tumours beyond a threshold size, has focused attention on the therapeutic potential of agents that prevent angiogenesis. The multistep nature...
3.
Griggs J, Brindle K, Metcalfe J, Hill S, Smith G, Beauregard D, et al.
Int J Oncol
. 2001 Sep;
19(4):821-5.
PMID: 11562761
The requirement for tumour vascularisation to permit the expansion of solid tumours beyond a threshold size of approximately 1 mm diameter has focussed attention on anti-vascular and anti-angiogenic agents for...
4.
Reckless J, Rubin E, Verstuyft J, Metcalfe J, Grainger D
J Vasc Res
. 2001 Jun;
38(3):256-65.
PMID: 11399898
The introduction of a range of different genetic modifications in mice results in altered lipoprotein metabolism and the development of vascular lipid lesions. At present, however, it is unclear to...
5.
Martin K, Metcalfe J, Kemp P
Mech Dev
. 2001 May;
103(1-2):149-51.
PMID: 11335124
Klf9 and Klf13 are members of the C(2)H(2) zinc finger family of transcription factors that are thought to be involved in regulating basal transcription. The mRNA localization of Klf9 and...
6.
Clark K, Cary N, Grace A, Metcalfe J
Arterioscler Thromb Vasc Biol
. 2001 Apr;
21(4):555-9.
PMID: 11304472
A somatic mutation within a microsatellite polyA tract in the coding region of the type II transforming growth factor (TGF)-beta receptor gene was reported to occur in human atherosclerotic and...
7.
Griggs J, Hesketh R, Smith G, Brindle K, Metcalfe J, Thomas G, et al.
Br J Cancer
. 2001 Mar;
84(6):832-5.
PMID: 11259100
Combretastatin-A4 phosphate (cis-CA-4) is a tubulin-binding agent currently undergoing clinical trials as an anti-tumour drug. We have investigated whether CA-4 functions as a tumour-specific anti-vascular agent using the hyperplastic thyroid...
8.
Clarke S, Schofield P, Grace A, Metcalfe J, Kirschenlohr H
Circulation
. 2001 Mar;
103(11):1497-502.
PMID: 11257075
Background: Tamoxifen and its analogues act as selective estrogen receptor modulators (SERMs) in women, with estrogen-like activities on some plasma cardiovascular risk factors (eg, lipoproteins). Effects of SERMs on men...
9.
Lucke C, Philpott A, Metcalfe J, Thompson A, Hughes-Davies L, Kemp P, et al.
Cancer Res
. 2001 Feb;
61(2):482-5.
PMID: 11212236
Members of the transforming growth factor beta (TGF-beta) family are potent inhibitors of the growth of many epithelial cell types. Transmembrane signaling by TGF-beta occurs via a complex of the...
10.
Ellis P, Chen Q, Barker P, Metcalfe J, Kemp P
Arterioscler Thromb Vasc Biol
. 2000 Aug;
20(8):1912-9.
PMID: 10938011
Nephroblastoma overexpressed (NOV) is a member of the CCN family (connective tissue growth factor, CYR61, and NOV) of proteins that are involved in regulating the proliferation, differentiation, and adhesion of...