J C H Hardwick
Overview
Explore the profile of J C H Hardwick including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
449
Followers
0
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Recent Articles
1.
Suerink M, Wimmer K, Brugieres L, Colas C, Gallon R, Ripperger T, et al.
Fam Cancer
. 2020 Jul;
20(1):67-73.
PMID: 32613597
No abstract available.
2.
Bronsgeest K, Huisman J, Langers A, Boonstra J, Schenk B, de Vos Tot Nederveen Cappel W, et al.
Int J Colorectal Dis
. 2017 Sep;
32(12):1711-1717.
PMID: 28884225
Background: Endoscopic mucosal resection (EMR) has been proven to be safe and effective for the treatment of colorectal adenomas. However, data are limited on the safety of this technique for...
3.
Backes Y, Moons L, van Bergeijk J, Berk L, Ter Borg F, Ter Borg P, et al.
BMC Gastroenterol
. 2016 May;
16(1):56.
PMID: 27229709
Background: Endoscopic mucosal resection (EMR) is currently the most used technique for resection of large distal colorectal polyps. However, in large lesions EMR can often only be performed in a...
4.
Paauwe M, Heijkants R, Oudt C, van Pelt G, Cui C, Theuer C, et al.
Oncogene
. 2016 Jan;
35(31):4069-79.
PMID: 26804178
Endoglin, a transforming growth factor-β co-receptor, is highly expressed on angiogenic endothelial cells in solid tumors. Therefore, targeting endoglin is currently being explored in clinical trials for anti-angiogenic therapy. In...
5.
Voorneveld P, Kodach L, Jacobs R, van Noesel C, Peppelenbosch M, Korkmaz K, et al.
Br J Cancer
. 2014 Nov;
112(1):122-30.
PMID: 25393365
Background: Constitutive Wnt activation is essential for colorectal cancer (CRC) initiation but also underlies the cancer stem cell phenotype, metastasis and chemosensitivity. Importantly Wnt activity is still modulated as evidenced...
6.
Voorneveld P, Stache V, Jacobs R, Smolders E, Sitters A, Liesker A, et al.
Br J Cancer
. 2013 Aug;
109(7):1805-12.
PMID: 23969729
Background: The expression of SMAD4, the central component of the transforming growth factor-β (TGF-β) and bone morphogenetic protein (BMP) signalling pathways, is lost in 50% of pancreatic cancers and is...
7.
Langers A, Verspaget H, Hawinkels L, Kubben F, van Duijn W, van der Reijden J, et al.
Br J Cancer
. 2012 Apr;
106(9):1495-8.
PMID: 22472880
Background: Upregulation of the matrix metalloproteinases MMP-2 and MMP-9 in various cancers has been associated with worse survival of the patients. Methods: We assessed MMP-2 and MMP-9 levels in normal...
8.
Heijmans J, Buller N, Hoff E, Dihal A, van der Poll T, van Zoelen M, et al.
Oncogene
. 2012 Apr;
32(9):1202-6.
PMID: 22469986
Development of colon cancer is a multistep process that is regulated by intrinsic and extrinsic cellular signals. Extrinsic factors include molecular patterns that are derived from either pathogens (PAMPs) or...
9.
Langers A, de Vos Tot Nederveen Cappel W, Veenendaal R, Bonsing B, Hardwick J, Vasen H
Endoscopy
. 2008 Aug;
40(9):773-4.
PMID: 18716983
Patients with familial adenomatous polyposis (FAP) have a 5%-10% lifetime risk of developing duodenal cancer. In severe duodenal polyposis, pancreaticoduodenectomy according to Whipple has been considered the only way to...
10.
van den Broek F, Fockens P, van Eeden S, Reitsma J, Hardwick J, Stokkers P, et al.
Gut
. 2008 Mar;
57(8):1083-9.
PMID: 18367559
Background: Endoscopic tri-modal imaging (ETMI) incorporates white light endoscopy (WLE), autofluorescence imaging (AFI) and narrow-band imaging (NBI). Aims: To assess the value of ETMI for the detection and classification of...