J C GAUTIER
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Explore the profile of J C GAUTIER including associated specialties, affiliations and a list of published articles.
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Articles
167
Citations
730
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Recent Articles
1.
GAUTIER J, Holzhaeuser D, Markovic J, Gremaud E, Schilter B, Turesky R
Free Radic Biol Med
. 2001 May;
30(10):1089-98.
PMID: 11369498
Ochratoxin A (OTA) is a mycotoxin found in some cereal and grain products. It is a potent renal carcinogen in male rats, although its mode of carcinogenic action is not...
2.
Gervot L, Rochat B, GAUTIER J, Bohnenstengel F, Kroemer H, de Berardinis V, et al.
Pharmacogenetics
. 1999 Sep;
9(3):295-306.
PMID: 10471061
Human cytochrome (CYP)2B6 cDNA was cloned and expressed in bacteria and in yeast. Its expression in Saccharomyces cerevisiae enabled us to obtain, at a high level, an active yeast-expressed CYP2B6...
3.
Gabaude C, Guillot M, GAUTIER J, Saudemon P, Chulia D
J Pharm Sci
. 1999 Jul;
88(7):725-30.
PMID: 10393572
Compressibility properties of pharmaceutical materials are widely characterized by measuring the volume reduction of a powder column under pressure. Experimental data are commonly analyzed using the Heckel model from which...
4.
Kramer S, GAUTIER J, Saudemon P
Pharm Res
. 1998 Aug;
15(8):1310-3.
PMID: 9706067
No abstract available.
5.
Pompon D, GAUTIER J, Perret A, Truan G, Urban P
J Hepatol
. 1997 Jan;
26 Suppl 2:81-5.
PMID: 9204413
An overview of current heterologous expression systems for xenobiotic metabolising enzymes is given with a special emphasis on the yeast expression system. In a first part, basic properties and relative...
6.
GAUTIER J, Lecoeur S, Cosme J, Perret A, Urban P, Beaune P, et al.
Pharmacogenetics
. 1996 Dec;
6(6):489-99.
PMID: 9014198
The metabolism of benzo[a]pyrene (B[a]P) and its proximate mutagen B[a]P-7,8-dihydrodiol (7,8-diol) was investigated in the presence of human microsomal epoxide hydrolase and P450 1A1, 1A2, 2C8, 2C9, 2C18, 2C19, 2D6...
7.
GAUTIER J, Urban P, Beaune P, Pompon D
Chem Res Toxicol
. 1996 Mar;
9(2):418-25.
PMID: 8839044
Human cytochrome P450 1A1 (1A1) and microsomal epoxide hydrolase (mEH)-dependent metabolic activation of benzo[a]pyrene (BP) have been reconstituted with microsomes from yeast cells expressing the two enzymes. The formation of...
8.
Belloc C, Baird S, Cosme J, Lecoeur S, GAUTIER J, Challine D, et al.
Toxicology
. 1996 Jan;
106(1-3):207-19.
PMID: 8571393
Cytochromes P450 (CYP) constitute a superfamily of enzymes involved in the metabolism of xenobiotics. Within the same subfamily, the isoforms present strong similarities, making them difficult to characterize and differentiate....
9.
Lecoeur S, GAUTIER J, Belloc C, Gauffre A, Beaune P
Methods Enzymol
. 1996 Jan;
272:76-85.
PMID: 8791764
No abstract available.
10.
Pompon D, Perret A, Bellamine A, Laine R, GAUTIER J, Urban P
Toxicol Lett
. 1995 Dec;
82-83:815-22.
PMID: 8597147
The first generation of yeast expression systems relies on inducible expression cassettes borne by multicopy plasmids for production of unmodified human P450s and on the endogenous NADPH-P450 reductase to support...