Pharmacogenetics
Overview
Pharmacogenetics is a scientific journal, published since 1991 in English. The journal's country of origin is United Kingdom and its primary focus areas are pharmacology and genetics.
Details
Details
Abbr.
Pharmacogenetics
Start
1991
End
2004
Frequency
Monthly, 2003-2004
p-ISSN
0960-314X
Country
United Kingdom
Language
English
Specialties
Pharmacology
Genetics
Genetics
Recent Articles
1.
Paynter R, Hankinson S, Colditz G, Hunter D, De Vivo I
Pharmacogenetics
. 2004 Dec;
14(12):851-6.
PMID: 15608564
Endogenous oestrogens play a crucial role in endometrial cancer pathogenesis, with most endometrial cancer risk factors causing an increase in oestrogens. Adipose tissue, where androgens are converted to oestrogens by...
2.
Yin O, Tomlinson B, Waye M, Chow A, Chow M
Pharmacogenetics
. 2004 Dec;
14(12):841-50.
PMID: 15608563
Objective: Ginkgo biloba was found to exert a significant inductive effect on CYP2C19 activity. This study was designed to investigate the potential herb-drug interaction between G. biloba and omeprazole, a...
3.
McDonald D, Alp N, Channon K
Pharmacogenetics
. 2004 Dec;
14(12):831-9.
PMID: 15608562
The G894T endothelial nitric oxide synthase (eNOS) polymorphism results in a Glu to Asp substitution at position 298. This position is located externally on the protein and as the regulation...
4.
Foucher C, Rattier S, Flavell D, Talmud P, Humphries S, Kastelein J, et al.
Pharmacogenetics
. 2004 Dec;
14(12):823-9.
PMID: 15608561
Objective: The association between polymorphisms in candidate genes related to lipoprotein metabolism and the reduction in plasma triglyceride (TG) in response to fenofibrate treatment was evaluated in subjects with type...
5.
King B, Khan T, Aithal G, Kamali F, Daly A
Pharmacogenetics
. 2004 Dec;
14(12):813-22.
PMID: 15608560
Objectives: To assess whether CYP2C9 alleles other than CYP2C9*2 and *3 are associated with a low-warfarin dose requirement and the relevance of upstream CYP2C9 polymorphisms to dose requirement and metabolism....
6.
Lin Z, Walther D, Yu X, Drgon T, Uhl G
Pharmacogenetics
. 2004 Dec;
14(12):805-11.
PMID: 15608559
Objective And Methods: 5-Hydroxytryptamine (serotonin) receptor 2B (HTR2B) is involved in brain development. Although expressed in the human brain, HTR2B has not been investigated much for its role in higher...
7.
Yuferov V, Fussell D, LaForge K, Nielsen D, Gordon D, Ho A, et al.
Pharmacogenetics
. 2004 Dec;
14(12):793-804.
PMID: 15608558
The kappa opioid receptor (KOR) plays a role in stress responsivity, opiate withdrawal and responses to cocaine. KOR activation by its endogenous ligand dynorphin A(1-17) decreases basal and drug-induced striatal...
8.
Etienne M, Formento J, Chazal M, Francoual M, Magne N, Formento P, et al.
Pharmacogenetics
. 2004 Dec;
14(12):785-92.
PMID: 15608557
Methylenetetrahydrofolate reductase (MTHFR) controls intracellular CH2FH4 concentrations (required for optimal fluoropyrimidine efficacy) by irreversibly converting CH2FH4 into 5-methyltetrahydrofolate. MTHFR 677C>T and 1298A>C polymorphisms are linked to altered enzyme activity. Thus,...
9.
Watson M, Pimenta J, Spreen W, Hernandez J
Pharmacogenetics
. 2004 Nov;
14(11):783-4.
PMID: 15564887
No abstract available.
10.
Gearry R, Roberts R, Barclay M, Kennedy M
Pharmacogenetics
. 2004 Nov;
14(11):779-81.
PMID: 15564886
A 94C>A missense mutation in the ITPA gene which encodes inosine triphosphate pyrophosphatase has been associated with adverse effects from azathioprine, specifically flu-like symptoms, pancreatitis and rash. We hypothesized that...