J Bralet
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Explore the profile of J Bralet including associated specialties, affiliations and a list of published articles.
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Articles
102
Citations
358
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Recent Articles
1.
Bralet J, Schwartz J
Trends Pharmacol Sci
. 2001 Mar;
22(3):106-9.
PMID: 11239563
No abstract available.
2.
Laurent S, Boutouyrie P, Azizi M, Marie C, Gros C, Schwartz J, et al.
Hypertension
. 2000 May;
35(5):1148-53.
PMID: 10818079
The aim of this study was to assess the antihypertensive activity of fasidotril, a dual inhibitor of neprilysin (NEP) and angiotensin I-converting enzyme (ACE), in various models of hypertension in...
3.
Marie C, Mossiat C, Gros C, Schwartz J, Lecomte J, Bralet J
Cardiovasc Res
. 1999 Aug;
41(3):544-53.
PMID: 10435026
Objective: Two hormonal systems with opposite effects are activated in congestive heart failure: the renin-angiotensin system that promotes vasoconstriction, cardiac hypertrophy and salt retention, and the atrial natriuretic factor (ANF),...
4.
Marie C, Mossiat C, Lecomte J, Bralet J
Pharmacology
. 1998 Jul;
56(6):291-6.
PMID: 9654215
The acute diuretic and natriuretic effects of fasidotrilat, a mixed inhibitor of neutral endopeptidase (NEP) and angiotensin I-converting enzyme (ACE) were evaluated in control and myocardial-infarcted rats. Fasidotrilat injection (10...
5.
Marie C, Mossiat C, Gros C, Monteil T, Bralet J
Cardiovasc Drugs Ther
. 1996 Nov;
10(5):593-8.
PMID: 8950076
Myocardial infarction was induced by rats by ligation of the left coronary artery. Treatment with TM1, a prodrug of SQ 28,603, an inhibitor of neutral endopeptidase (NEP, EC 3.4.24.11), was...
6.
Oubidar M, Marie C, Mossiat C, Bralet J
J Mol Cell Cardiol
. 1996 Aug;
28(8):1769-76.
PMID: 8877786
Elevation of cell iron content was produced by use of a lipophilic iron ligand, 8-hydroxyquinoline (HQ), capable of transferring catalytically active iron into cells. The Fe(3+)-HQ complex labeled with 59Fe...
7.
Oubidar M, Boquillon M, Marie C, Bouvier C, Beley A, Bralet J
Free Radic Biol Med
. 1996 Jan;
21(6):763-9.
PMID: 8902522
The effect of artificially elevated cell iron content on oxygen-derived free radical production was assessed in brain slices by use of an iron ligand, 8-hydroxyquinoline (HQ). The iron complex Fe(3+)-HQ...
8.
Gueldry S, Bralet J
Metab Brain Dis
. 1995 Dec;
10(4):293-301.
PMID: 8847993
DL-1,3-butanediol (DL-BD) is an ethanol dimer which affords cerebral protection in various experimental models of hypoxia and ischemia but its mechanism of action is unknown. DL-BD is a ketogenic alcohol...
9.
Marie C, Mossiat C, Lecomte J, Schwartz J, Bralet J
J Pharmacol Exp Ther
. 1995 Dec;
275(3):1324-31.
PMID: 8531099
The aim of the present study was to determine, in rats with myocardial infarction, the systemic and cardiac hemodynamic effects of aladotrilat and of its prodrug, aladotril, both of which...
10.
Bralet J, Marie C, Mossiat C, Lecomte J, Gros C, Schwartz J
J Pharmacol Exp Ther
. 1994 Jul;
270(1):8-14.
PMID: 8035346
The aim of the study was to compare, in a rat model of congestive heart failure, the effect of captopril, a selective angiotensin-converting enzyme (ACE; EC 3.4.15.1) inhibitor, to that...