J B Clements
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Explore the profile of J B Clements including associated specialties, affiliations and a list of published articles.
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77
Citations
2414
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Recent Articles
1.
Phelan A, Clements J
Methods Mol Med
. 2011 Mar;
10:193-203.
PMID: 21374230
During lytic virus replication, herpes simplex virus (HSV) exhibits a closely regulated pattern of viral gene expression and of DNA replication, resulting in virion production (1). Broadly, HSV genes can...
2.
Smith R, Malik P, Clements J
Biochem Soc Trans
. 2005 May;
33(Pt 3):499-501.
PMID: 15916551
The herpes simplex virus 1 ICP27 is an essential, highly conserved protein involved in various steps of herpes simplex virus 1 gene regulation as well as in the shut-off of...
3.
Koffa M, Clements J, Izaurralde E, Wadd S, Wilson S, Mattaj I, et al.
EMBO J
. 2001 Oct;
20(20):5769-78.
PMID: 11598019
The role of herpes simplex virus ICP27 protein in mRNA export is investigated by microinjection into Xenopus laevis oocytes. ICP27 dramatically stimulates the export of intronless viral mRNAs, but has...
4.
Bryant H, Wadd S, Lamond A, Silverstein S, Clements J
J Virol
. 2001 Apr;
75(9):4376-85.
PMID: 11287586
The multifunctional herpes simplex virus type 1 (HSV-1) protein IE63 (ICP27) interacts with the essential pre-mRNA splicing factor, spliceosome-associated protein 145 (SAP145), and in infected cells IE63 and SAP145 colocalize....
5.
Zachos G, Koffa M, Preston C, Clements J, Conner J
J Virol
. 2001 Feb;
75(6):2710-28.
PMID: 11222695
Wild-type (wt) herpes simplex virus type 1 (HSV-1) suppresses cell death. We investigated the apoptotic pathways triggered during infection with mutant viruses tsk and 27lacZ (which lack functional ICP4 and...
6.
Bryant H, Matthews D, Wadd S, Scott J, Kean J, Graham S, et al.
J Virol
. 2000 Nov;
74(23):11322-8.
PMID: 11070032
The herpes simplex virus type 1 (HSV-1) immediate-early gene IE63 (ICP27), the only HSV-1 regulatory gene with a homologue in every mammalian and avian herpesvirus sequenced so far, is a...
7.
Koffa M, Graham S, Takagaki Y, Manley J, Clements J
Proc Natl Acad Sci U S A
. 2000 Apr;
97(9):4677-82.
PMID: 10781073
In human papillomaviruses, expression of the late genes L1 and L2, encoding the capsid proteins, is restricted to the upper layers of the infected epithelium. A 79-nt GU-rich negative regulatory...
8.
Wadd S, Bryant H, Filhol O, Scott J, Hsieh T, Everett R, et al.
J Biol Chem
. 1999 Oct;
274(41):28991-8.
PMID: 10506147
Herpes simplex virus type 1 (HSV-1), the prototype alpha-herpesvirus, causes several prominent diseases. The HSV-1 immediate early (IE) protein IE63 (ICP27) is the only regulatory gene with a homologue in...
9.
Phelan A, Clements J
J Gen Virol
. 1997 Dec;
78 ( Pt 12):3327-31.
PMID: 9400984
Herpes simplex virus type 1 (HSV-1) immediate early protein IE63, an essential nuclear protein, is pleiotropic in function and, at the post-transcriptional level, inhibits RNA splicing, interacts with cellular splicing...
10.
Chase C, Layman T, Barker D, Clements J
J Vasc Surg
. 1997 May;
25(5):936-40.
PMID: 9152324
A traumatic pseudoaneurysm of the suprarenal abdominal aorta was diagnosed in a 58-year-old man 32 years after he received a gunshot wound to the abdomen. Epigastric pain and obstructive jaundice...