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J Anthony Graves

Explore the profile of J Anthony Graves including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 195
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Recent Articles
1.
Casinelli G, LaRosa J, Sharma M, Cherok E, Banerjee S, Branca M, et al.
Cell Death Discov . 2016 Dec; 2:16082. PMID: 28028439
N-Myc is a global transcription factor that regulates the expression of genes involved in a number of essential cellular processes including: ribosome biogenesis, cell cycle and apoptosis. Upon deregulation, N-Myc...
2.
Sarin M, Wang Y, Zhang F, Rothermund K, Zhang Y, Lu J, et al.
Cell Death Dis . 2013 Jun; 4:e670. PMID: 23764851
The c-Myc (Myc) oncoprotein regulates numerous phenotypes pertaining to cell mass, survival and metabolism. Glycolysis, oxidative phosphorylation (OXPHOS) and mitochondrial biogenesis are positively controlled by Myc, with myc-/- rat fibroblasts...
3.
Graves J, Wang Y, Sims-Lucas S, Cherok E, Rothermund K, Branca M, et al.
PLoS One . 2012 May; 7(5):e37699. PMID: 22629444
Although the c-Myc (Myc) oncoprotein controls mitochondrial biogenesis and multiple enzymes involved in oxidative phosphorylation (OXPHOS), the coordination of these events and the mechanistic underpinnings of their regulation remain largely...
4.
Graves J, Rothermund K, Wang T, Qian W, Van Houten B, Prochownik E
PLoS One . 2010 Nov; 5(10):e13717. PMID: 21060841
Deregulation of c-Myc (Myc) occurs in many cancers. In addition to transforming various cell types, Myc also influences additional transformation-associated cellular phenotypes including proliferation, survival, genomic instability, reactive oxygen species...
5.
Graves J, Metukuri M, Scott D, Rothermund K, Prochownik E
J Biol Chem . 2008 Dec; 284(10):6520-9. PMID: 19098005
Peroxiredoxins (Prxs) are highly conserved proteins found in most organisms, where they function primarily to scavenge reactive oxygen species (ROS). Loss of the most ubiquitous member of the family, Prx1,...
6.
Jiranek V, Graves J, Henry S
Microbiology (Reading) . 1998 Nov; 144 ( Pt 10):2739-2748. PMID: 9802015
Key factors which impact on the biosynthesis and subsequent fate of the phospholipid precursor inositol were studied as a function of growth phase in the yeast Saccharomyces cerevisiae. Both wild-type...