J Andrew Alspaugh
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Explore the profile of J Andrew Alspaugh including associated specialties, affiliations and a list of published articles.
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84
Citations
2341
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Recent Articles
1.
Probst C, Denning-Jannace C, du Plooy L, Giamberardino C, Asfaw Y, Franz K, et al.
bioRxiv
. 2024 Dec;
PMID: 39713408
Importance: Copper is an essential micronutrient required for survival in all kingdoms of life as it is used as a catalytic cofactor for many essential processes in the cell. In...
2.
Alspaugh J
Proc Natl Acad Sci U S A
. 2024 Oct;
121(43):e2417587121.
PMID: 39401369
No abstract available.
3.
du Plooy L, Telzrow C, Nichols C, Probst C, Castro-Lopez N, Wormley Jr F, et al.
mBio
. 2024 Sep;
15(10):e0098124.
PMID: 39235249
Importance: Microbial proteins involved in human infectious diseases often need to be modified by specific chemical additions to be fully functional. Here, we explore the role of a particular protein...
4.
Pianalto K, Telzrow C, Brown Harding H, Brooks J, Granek J, Gushiken-Ibanez E, et al.
mBio
. 2024 Aug;
15(10):e0206024.
PMID: 39189745
During mammalian colonization and infection, microorganisms must be able to rapidly sense and adapt to changing environmental conditions including alterations in extracellular pH. The fungus-specific Rim/Pal signaling pathway is one...
5.
Pianalto K, Telzrow C, Brown Harding H, Brooks J, Granek J, Gushiken-Ibanez E, et al.
bioRxiv
. 2024 Jul;
PMID: 39026808
During mammalian colonization and infection, microorganisms must be able to rapidly sense and adapt to changing environmental conditions including alterations in extracellular pH. The fungus-specific Rim/Pal signaling pathway is one...
6.
Upadhya R, Probst C, Alspaugh J, Lodge J
Methods Mol Biol
. 2024 May;
2775:277-303.
PMID: 38758325
Cryptococcus neoformans is an opportunistic human fungal pathogen capable of surviving in a wide range of environments and hosts. It has been developed as a model organism to study fungal...
7.
OMeara M, Rapala J, Nichols C, Alexandre A, Billmyre R, Steenwyk J, et al.
PLoS Genet
. 2024 Feb;
20(2):e1011158.
PMID: 38359090
Elucidating gene function is a major goal in biology, especially among non-model organisms. However, doing so is complicated by the fact that molecular conservation does not always mirror functional conservation,...
8.
OMeara M, Rapala J, Nichols C, Alexandre C, Billmyre R, Steenwyk J, et al.
bioRxiv
. 2023 Aug;
PMID: 37645941
Elucidating gene function is a major goal in biology, especially among non-model organisms. However, doing so is complicated by the fact that molecular conservation does not always mirror functional conservation,...
9.
Probst C, Hallas-Moller M, Ipsen J, Brooks J, Andersen K, Haon M, et al.
PLoS Pathog
. 2023 Apr;
19(4):e1010946.
PMID: 37099613
Fungi often adapt to environmental stress by altering their size, shape, or rate of cell division. These morphological changes require reorganization of the cell wall, a structural feature external to...
10.
Telzrow C, Esher Righi S, Cathey J, Granek J, Alspaugh J
Front Physiol
. 2023 Mar;
14:1150272.
PMID: 36969606
Microbial pathogens undergo significant physiological changes during interactions with the infected host, including alterations in metabolism and cell architecture. The Mar1 protein is required for the proper ordering of the...