Ivan K H Poon
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Explore the profile of Ivan K H Poon including associated specialties, affiliations and a list of published articles.
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72
Citations
3192
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Recent Articles
1.
Hsueh W, Wu Y, Weng M, Liu S, Santavanond J, Liu Y, et al.
Adv Sci (Weinh)
. 2024 Dec;
12(7):e2411538.
PMID: 39739600
Pannexin 1 (PANX1) forms cell-surface channels capable of releasing signaling metabolites for diverse patho-physiological processes. While inhibiting dysregulated PANX1 has been proposed as a therapeutic strategy for many pathological conditions,...
2.
Atkin-Smith G, Santavanond J, Light A, Rimes J, Samson A, Er J, et al.
Nat Commun
. 2024 Oct;
15(1):8802.
PMID: 39438460
Endothelial cells are integral components of all vasculature within complex organisms. As they line the blood vessel wall, endothelial cells are constantly exposed to a variety of molecular factors and...
3.
Shi B, Phan T, Poon I
Trends Cell Biol
. 2024 Oct;
PMID: 39438206
Communication between dying and neighbouring cells is vital to ensure appropriate processes such as tissue repair or inflammation are initiated in response to cell death. As a mechanism to aid...
4.
Day Z, Mayfosh A, Baxter A, Williams S, Hildebrand J, Rau T, et al.
Biomolecules
. 2024 May;
14(5).
PMID: 38785962
Here, we describe GS-9, a novel water-soluble fatty acid-based formulation comprising L-lysine and arachidonic acid, that we have shown to induce ferroptosis. GS-9 forms vesicle-like structures in solution and mediates...
5.
Dmello R, Palmieri M, Thilakasiri P, Doughty L, Nero T, Poh A, et al.
Cell Death Dis
. 2024 Apr;
15(4):255.
PMID: 38600086
Excessive STAT3 signalling via gp130, the shared receptor subunit for IL-6 and IL-11, contributes to disease progression and poor survival outcomes in patients with colorectal cancer. Here, we provide evidence...
6.
Nguyen T, Paone S, Baxter A, Mayfosh A, Phan T, Chan E, et al.
Atherosclerosis
. 2024 Apr;
392:117519.
PMID: 38581737
Background And Aims: Atherosclerosis is the primary underlying cause of myocardial infarction and stroke, which are the major causes of death globally. Heparanase (Hpse) is a pro-inflammatory extracellular matrix degrading...
7.
Santavanond J, Chiu Y, Tixeira R, Liu Z, Yap J, Chen K, et al.
Cell Death Dis
. 2024 Feb;
15(2):123.
PMID: 38336804
Discovery of new small molecules that can activate distinct programmed cell death pathway is of significant interest as a research tool and for the development of novel therapeutics for pathological...
8.
9.
Poon I, Ravichandran K
Annu Rev Pharmacol Toxicol
. 2023 Aug;
64:339-357.
PMID: 37585658
Rapid removal of apoptotic cells by phagocytes, a process known as efferocytosis, is key for the maintenance of tissue homeostasis, the resolution of inflammation, and tissue repair. However, impaired efferocytosis...
10.
Tanzer M, Tummers B, Poon I
Front Cell Dev Biol
. 2023 Apr;
11:1195775.
PMID: 37113768
No abstract available.