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Ivan I Senin

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Articles 35
Citations 590
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Recent Articles
1.
Chistyakov D, Tiulina V, Gancharova O, Baksheeva V, Goriainov S, Shebardina N, et al.
Int J Mol Sci . 2024 Dec; 25(23). PMID: 39684616
Autoimmune uveitis is a relapsing blind-causing ocular condition with complex pathogenesis that is not completely understood. There is a high demand for accurate animal models of experimental autoimmune uveitis (EAU)...
2.
Lunegova D, Gvozdev D, Senin I, Gudkova V, Sidorenko S, Tiulina V, et al.
FEBS J . 2024 Nov; 292(2):355-372. PMID: 39580658
Photodamage to the outer segments of photoreceptor cells and their impaired utilization by retinal pigment epithelium (RPE) cells contribute to the development of age-related macular degeneration (AMD) leading to blindness....
3.
Baksheeva V, Tiulina V, Iomdina E, Petrov S, Filippova O, Kushnarevich N, et al.
Int J Mol Sci . 2023 Apr; 24(8). PMID: 37108298
Primary open-angle glaucoma (POAG) is a frequent blindness-causing neurodegenerative disorder characterized by optic nerve and retinal ganglion cell damage most commonly due to a chronic increase in intraocular pressure. The...
4.
Chistyakov D, Gancharova O, Baksheeva V, Tiulina V, Goriainov S, Azbukina N, et al.
Biomedicines . 2020 Sep; 8(9). PMID: 32932827
Dry eye syndrome (DES) is characterized by decreased tear production and stability, leading to desiccating stress, inflammation and corneal damage. DES treatment may involve targeting the contributing inflammatory pathways mediated...
5.
Chistyakov D, Azbukina N, Astakhova A, Goriainov S, Chistyakov V, Tiulina V, et al.
Metabolomics . 2020 Feb; 16(2):27. PMID: 32052201
Introduction: Ocular inflammation is a key pathogenic factor in most blindness-causing visual disorders. It can manifest in the aqueous humor (AH) and tear fluid (TF) as alterations in polyunsaturated fatty...
6.
Chistyakov D, Baksheeva V, Tiulina V, Goriainov S, Azbukina N, Gancharova O, et al.
Int J Mol Sci . 2020 Jan; 21(3). PMID: 31973128
Ocular inflammation contributes to the pathogenesis of blind-causing retinal degenerative diseases, such as age-related macular degeneration (AMD) or photic maculopathy. Here, we report on inflammatory mechanisms that are associated with...
7.
Zernii E, Nazipova A, Nemashkalova E, Kazakov A, Gancharova O, Serebryakova M, et al.
Front Mol Neurosci . 2019 Jan; 11:474. PMID: 30666186
The excessive light illumination of mammalian retina is known to induce oxidative stress and photoreceptor cell death linked to progression of age-related macular degeneration. The photochemical damage of photoreceptors is...
8.
Zernii E, Gancharova O, Tiulina V, Zamyatnin Jr A, Philippov P, Baksheeva V, et al.
BMC Ophthalmol . 2018 Dec; 18(1):336. PMID: 30587174
Background: Cornea protects the eye against natural and anthropogenic ultraviolet (UV) damage and mechanical injury. Corneal incisions produced by UV lasers in ophthalmic surgeries are often complicated by oxidative stress...
9.
Baksheeva V, Tiulina V, Tikhomirova N, Gancharova O, Komarov S, Philippov P, et al.
Antioxidants (Basel) . 2018 Dec; 8(1). PMID: 30577635
Light-induced oxidation of lipids and proteins provokes retinal injuries and results in progression of degenerative retinal diseases, such as, for instance, iatrogenic photic maculopathies. Having accumulated over years retinal injuries...
10.
Vladimirov V, Zernii E, Baksheeva V, Wimberg H, Kazakov A, Tikhomirova N, et al.
Cell Calcium . 2018 Apr; 73:55-69. PMID: 29684785
Rod cell membranes contain cholesterol-rich detergent-resistant membrane (DRM) rafts, which accumulate visual cascade proteins as well as proteins involved in regulation of phototransduction such as rhodopsin kinase and guanylate cyclases....