Ivan Domenzain
Overview
Explore the profile of Ivan Domenzain including associated specialties, affiliations and a list of published articles.
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14
Citations
545
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Recent Articles
1.
Domenzain I, Lu Y, Wang H, Shi J, Lu H, Nielsen J
Proc Natl Acad Sci U S A
. 2025 Feb;
122(9):e2417322122.
PMID: 39999169
Development of efficient cell factories that can compete with traditional chemical production processes is complex and generally driven by case-specific strategies, based on the product and microbial host of interest....
2.
Chen Y, Gustafsson J, Rangel A, Anton M, Domenzain I, Kittikunapong C, et al.
Nat Protoc
. 2024 Jan;
19(3):629-667.
PMID: 38238583
Genome-scale metabolic models (GEMs) are computational representations that enable mathematical exploration of metabolic behaviors within cellular and environmental constraints. Despite their wide usage in biotechnology, biomedicine and fundamental studies, there...
3.
Ishchuk O, Domenzain I, Sanchez B, Muniz-Paredes F, Martinez J, Nielsen J, et al.
Proc Natl Acad Sci U S A
. 2022 Jul;
119(30):e2108245119.
PMID: 35858410
Heme is an oxygen carrier and a cofactor of both industrial enzymes and food additives. The intracellular level of free heme is low, which limits the synthesis of heme proteins....
4.
Domenzain I, Sanchez B, Anton M, Kerkhoven E, Millan-Oropeza A, Henry C, et al.
Nat Commun
. 2022 Jun;
13(1):3766.
PMID: 35773252
Genome-scale metabolic models (GEMs) have been widely used for quantitative exploration of the relation between genotype and phenotype. Streamlined integration of enzyme constraints and proteomics data into such models was...
5.
Montini N, Doughty T, Domenzain I, Fenton D, Baranov P, Harrington R, et al.
Microbiology (Reading)
. 2022 Mar;
168(3).
PMID: 35333706
It is important to understand the basis of thermotolerance in yeasts to broaden their application in industrial biotechnology. The capacity to run bioprocesses at temperatures above 40 °C is of...
6.
Lu H, Li F, Yuan L, Domenzain I, Yu R, Wang H, et al.
Mol Syst Biol
. 2021 Oct;
17(10):e10427.
PMID: 34676984
Yeasts are known to have versatile metabolic traits, while how these metabolic traits have evolved has not been elucidated systematically. We performed integrative evolution analysis to investigate how genomic evolution...
7.
Sanchez B, Lahtvee P, Campbell K, Kasvandik S, Yu R, Domenzain I, et al.
Proteomics
. 2021 Aug;
21(15):e2170095.
PMID: 34357672
No abstract available.
8.
Osterberg L, Domenzain I, Munch J, Nielsen J, Hohmann S, Cvijovic M
PLoS Comput Biol
. 2021 Apr;
17(4):e1008891.
PMID: 33836000
The interplay between nutrient-induced signaling and metabolism plays an important role in maintaining homeostasis and its malfunction has been implicated in many different human diseases such as obesity, type 2...
9.
Sanchez B, Lahtvee P, Campbell K, Kasvandik S, Yu R, Domenzain I, et al.
Proteomics
. 2021 Jan;
21(6):e2000093.
PMID: 33452728
Protein quantification via label-free mass spectrometry (MS) has become an increasingly popular method for predicting genome-wide absolute protein abundances. A known caveat of this approach, however, is the poor technical...
10.
Domenzain I, Li F, Kerkhoven E, Siewers V
FEMS Yeast Res
. 2021 Jan;
21(1).
PMID: 33428734
Metabolic network reconstructions have become an important tool for probing cellular metabolism in the field of systems biology. They are used as tools for quantitative prediction but also as scaffolds...