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Iti Saraav

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Recent Articles
1.
Greigert V, Saraav I, Son J, Zhu Y, Dayao D, Antia A, et al.
Gut Microbes . 2024 Jan; 16(1):2297897. PMID: 38189373
Cryptosporidiosis is a major cause of severe diarrheal disease in infants from resource poor settings. The majority of infections are caused by the human-specific pathogen and absence of in vitro...
2.
Greigert V, Saraav I, Son J, Dayao D, Antia A, Tzipori S, et al.
bioRxiv . 2023 Sep; PMID: 37693422
Cryptosporidiosis is a major cause of severe diarrheal disease in infants from resource poor settings. The majority of infections are caused by the human-specific pathogen and absence of in vitro...
3.
Saraav I, Sibley L
Microorganisms . 2023 Apr; 11(4). PMID: 37110479
Host immune responses are required for the efficient control of cryptosporidiosis. Immunity against infection has been best studied in mice, where it is mediated by both innate and adaptive immune...
4.
Saraav I, Cervantes-Barragan L, Olias P, Fu Y, Wang Q, Wang L, et al.
Proc Natl Acad Sci U S A . 2021 Aug; 118(36). PMID: 34462359
Oral infection with results in dysbiosis and enteritis, both of which revert to normal during chronic infection. However, whether infection leaves a lasting impact on mucosal responses remains uncertain. Here...
5.
Saraav I, Wang Q, Brown K, Sibley L
mSphere . 2019 Mar; 4(1). PMID: 30814319
Microneme (MIC) proteins play important roles in the recognition, adhesion, and invasion of host cells by Previous studies have shown that MIC proteins are highly immunogenic in the mouse and...
6.
Saraav I, Singh S, Pandey K, Sharma M, Sharma S
Tuberculosis (Edinb) . 2017 Aug; 106:16-24. PMID: 28802400
Cell wall of Mycobacterium tuberculosis (M.tb) is a major source of immunogenic proteins that can be tested as vaccine candidates. MymA (Rv3083), a 55 kDa M.tb flavin containing monooxygenase, is...
7.
Saraav I, Pandey K, Misra R, Singh S, Sharma M, Sharma S
Chem Biol Drug Des . 2016 Aug; 89(1):152-160. PMID: 27539124
Tuberculosis is a global health problem especially with the emergence of drug-resistant Mycobacterium tuberculosis strains, creating an urgent need to identify new drug targets. The mycobacterial cell wall is an...
8.
Saraav I, Pandey K, Sharma M, Singh S, Dutta P, Bhardwaj A, et al.
Infect Genet Evol . 2016 Jul; 44:182-189. PMID: 27389362
Limited efficacy of Bacillus Calmette-Guérin vaccine has raised the need to explore other immunogenic candidates to develop an effective vaccine against Mycobacterium tuberculosis (Mtb). Both CD4+ and CD8+ T cells...
9.
Saraav I, Singh S, Sharma S
Immunol Cell Biol . 2014 Jul; 92(9):741-6. PMID: 24983458
Mycobacterium tuberculosis (M. tuberculosis), the causative agent of tuberculosis, is an intracellular bacterium capable of surviving and persisting within host mononuclear cells. The host response against tubercle bacilli is dominated...
10.
Singh S, Saraav I, Sharma S
Vaccine . 2013 Dec; 32(6):712-6. PMID: 24300592
Tuberculosis remains a great health threat to the world among infectious diseases particularly with the advent of human immunodeficiency virus and emergence of drug resistant strains. In the light of...