Ismael Galve-Roperh
Overview
Explore the profile of Ismael Galve-Roperh including associated specialties, affiliations and a list of published articles.
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58
Citations
2758
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Recent Articles
1.
Quintero J, Diaz L, Galve-Roperh I, Bustos R, Leon M, Beltran S, et al.
Expert Opin Ther Targets
. 2024 Sep;
28(9):739-755.
PMID: 39317147
Introduction: This review highlights the critical role of the endocannabinoid system (ECS) in regulating neuropathic pain and explores the therapeutic potential of cannabinoids. Understanding the mechanisms of the ECS, including...
2.
Maroto I, Costas-Insua C, Berthoux C, Moreno E, Ruiz-Calvo A, Montero-Fernandez C, et al.
Nat Commun
. 2023 Apr;
14(1):2303.
PMID: 37085487
The type-1 cannabinoid receptor (CBR) is widely expressed in excitatory and inhibitory nerve terminals, and by suppressing neurotransmitter release, its activation modulates neural circuits and brain function. While the interaction...
3.
Sanchez-de la Torre A, Aguado T, Huerga-Gomez A, Santamaria S, Gentile A, Chara J, et al.
Cell Death Dis
. 2022 Jul;
13(7):585.
PMID: 35798697
Cannabinoids are known to modulate oligodendrogenesis and developmental CNS myelination. However, the cell-autonomous action of these compounds on oligodendroglial cells in vivo, and the molecular mechanisms underlying these effects have...
4.
Costas-Insua C, Moreno E, Maroto I, Ruiz-Calvo A, Bajo-Graneras R, Martin-Gutierrez D, et al.
J Neurosci
. 2021 Aug;
41(38):7924-7941.
PMID: 34353897
Cannabinoids, the bioactive constituents of cannabis, exert a wide array of effects on the brain by engaging Type 1 cannabinoid receptor (CBR). Accruing evidence supports that cannabinoid action relies on...
5.
Aguado T, Huerga-Gomez A, Sanchez-de la Torre A, Resel E, Chara J, Matute C, et al.
Br J Pharmacol
. 2021 Jul;
178(20):4176-4192.
PMID: 34216154
Background And Purpose: Research on demyelinating disorders aims to find novel molecules that are able to induce oligodendrocyte precursor cell differentiation to promote central nervous system remyelination and functional recovery....
6.
Paraiso-Luna J, Aguareles J, Martin R, Ayo-Martin A, Simon-Sanchez S, Garcia-Rincon D, et al.
Development
. 2020 Nov;
147(24).
PMID: 33168583
The endocannabinoid (eCB) system, via the cannabinoid CB receptor, regulates neurodevelopment by controlling neural progenitor proliferation and neurogenesis. CB receptor signalling drives corticofugal deep layer projection neuron development through the...
7.
Blazquez C, Ruiz-Calvo A, Bajo-Graneras R, Baufreton J, Resel E, Varilh M, et al.
Autophagy
. 2020 Sep;
16(12):2289-2291.
PMID: 32981464
The recreational and medical use of cannabis is largely increasing worldwide. Cannabis use, however, can cause adverse side effects, so conducting innovative studies aimed to understand and potentially reduce cannabis-evoked...
8.
Huerga-Gomez A, Aguado T, Sanchez-de la Torre A, Bernal-Chico A, Matute C, Mato S, et al.
Glia
. 2020 Sep;
69(3):532-545.
PMID: 32956517
Δ -Tetrahydrocannabinol (THC), the main bioactive compound found in the plant Cannabis sativa, exerts its effects by activating cannabinoid receptors present in many neural cells. Cannabinoid receptors are also physiologically...
9.
Blazquez C, Ruiz-Calvo A, Bajo-Graneras R, Baufreton J, Resel E, Varilh M, et al.
Elife
. 2020 Aug;
9.
PMID: 32773031
The use of cannabis is rapidly expanding worldwide. Thus, innovative studies aimed to identify, understand and potentially reduce cannabis-evoked harms are warranted. Here, we found that Δ-tetrahydrocannabinol, the psychoactive ingredient...
10.
Fernandez-Ruiz J, Galve-Roperh I, Sagredo O, Guzman M
Eur Neuropsychopharmacol
. 2020 Feb;
36:217-234.
PMID: 32057592
Cannabis use induces a plethora of actions on the CNS via its active chemical ingredients, the so-called phytocannabinoids. These compounds have been frequently associated with the intoxicating properties of cannabis...