Ishara F Azmi
Overview
Explore the profile of Ishara F Azmi including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
291
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0
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Recent Articles
1.
Tseng C, Dean S, Davies B, Azmi I, Pashkova N, Payne J, et al.
J Cell Biol
. 2021 Jul;
220(8).
PMID: 34259833
No abstract available.
2.
Bro1 stimulates Vps4 to promote intralumenal vesicle formation during multivesicular body biogenesis
Tseng C, Dean S, Davies B, Azmi I, Pashkova N, Payne J, et al.
J Cell Biol
. 2021 Jun;
220(8).
PMID: 34160559
Endosomal sorting complexes required for transport (ESCRT-0, -I, -II, -III) execute cargo sorting and intralumenal vesicle (ILV) formation during conversion of endosomes to multivesicular bodies (MVBs). The AAA-ATPase Vps4 regulates...
3.
Warner M, Azmi I, Kang S, Zhao Y, Bell S
J Biol Chem
. 2017 Oct;
292(52):21417-21430.
PMID: 29074622
In eukaryotes, DNA replication initiates from multiple origins of replication for timely genome duplication. These sites are selected by origin licensing, during which the core enzyme of the eukaryotic DNA...
4.
Azmi I, Watanabe S, Maloney M, Kang S, Belsky J, MacAlpine D, et al.
Elife
. 2017 Mar;
6.
PMID: 28322723
Eukaryotic replication origin licensing, activation and timing are influenced by chromatin but a mechanistic understanding is lacking. Using reconstituted nucleosomal DNA replication assays, we assessed the impact of nucleosomes on...
5.
Norgan A, Davies B, Azmi I, Schroeder A, Payne J, Lynch G, et al.
J Biol Chem
. 2013 Jul;
288(36):26147-26156.
PMID: 23880759
The endosomal sorting complexes required for transport (ESCRTs) impact multiple cellular processes including multivesicular body sorting, abscission, and viral budding. The AAA-ATPase Vps4 is required for ESCRT function, and its...
6.
Davies B, Azmi I, Payne J, Shestakova A, Horazdovsky B, Babst M, et al.
Mol Biol Cell
. 2010 Aug;
21(19):3396-408.
PMID: 20702581
ESCRT-III undergoes dynamic assembly and disassembly to facilitate membrane exvagination processes including multivesicular body (MVB) formation, enveloped virus budding, and membrane abscission during cytokinesis. The AAA-ATPase Vps4 is required for...
7.
Davies B, Azmi I, Katzmann D
Biochem Soc Trans
. 2009 Jan;
37(Pt 1):143-5.
PMID: 19143619
MVB (multivesicular body) formation occurs when the limiting membrane of an endosome invaginates into the intraluminal space and buds into the lumen, bringing with it a subset of transmembrane cargoes....
8.
Azmi I, Davies B, Xiao J, Babst M, Xu Z, Katzmann D
Dev Cell
. 2008 Jan;
14(1):50-61.
PMID: 18194652
The AAA-ATPase Vps4 is critical for function of the MVB sorting pathway, which in turn impacts cellular phenomena ranging from receptor downregulation to viral budding to cytokinesis. Vps4 dissociates ESCRTs...
9.
Xiao J, Xia H, Zhou J, Azmi I, Davies B, Katzmann D, et al.
Dev Cell
. 2008 Jan;
14(1):37-49.
PMID: 18194651
The MVB pathway plays essential roles in several eukaryotic cellular processes. Proper function of the MVB pathway requires reversible membrane association of the ESCRTs, a process catalyzed by Vps4 ATPase....