Isabelle Van Seuningen
Overview
Explore the profile of Isabelle Van Seuningen including associated specialties, affiliations and a list of published articles.
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Articles
117
Citations
3788
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Recent Articles
1.
Stoup N, Liberelle M, Lebegue N, Van Seuningen I
Trends Pharmacol Sci
. 2024 May;
45(6):552-576.
PMID: 38797570
The epidermal growth factor receptor (EGFR) family is a class of transmembrane proteins, highly regarded as anticancer targets due to their pivotal role in various malignancies. Standard cancer treatments targeting...
2.
Nussinov R, Weichhart T, Dlamini Z, Gibbons D, Van Seuningen I, Konen J, et al.
Trends Pharmacol Sci
. 2024 May;
45(6):467-471.
PMID: 38760267
No abstract available.
3.
Bourdon E, Swierczewski T, Goujon M, Boukrout N, Fellah S, Van der Hauwaert C, et al.
Cancers (Basel)
. 2024 Jan;
16(2).
PMID: 38254882
While the transmembrane glycoprotein mucin 1 (MUC1) is clustered at the apical borders of normal epithelial cells, with transformation and loss of polarity, MUC1 is found at high levels in...
4.
Quilbe A, Mustapha R, Duchene B, Kumar A, Werkmeister E, Leteurtre E, et al.
Front Immunol
. 2023 Dec;
14:1267279.
PMID: 38098486
Background: Pancreatic adenocarcinoma (PDAC) is a devastating disease with an urgent need for therapeutic innovation. Immune checkpoint inhibition has shown promise in a variety of solid tumors, but most clinical...
5.
Cicero J, Trouvilliez S, Palma M, Ternier G, Decoster L, Happernegg E, et al.
Exp Hematol Oncol
. 2023 Dec;
12(1):104.
PMID: 38072918
Background: Triple-Negative Breast Cancer is particularly aggressive, and its metastasis to the brain has a significant psychological impact on patients' quality of life, in addition to reducing survival. The development...
6.
Jannin A, Dessein A, Do Cao C, Vantyghem M, Chevalier B, Van Seuningen I, et al.
Front Endocrinol (Lausanne)
. 2023 Nov;
14:1248575.
PMID: 37908747
Introduction: Reprogramming of cellular metabolism is now a hallmark of tumorigenesis. In recent years, research on pancreatic neuroendocrine tumors (pNETs) has focused on genetic and epigenetic modifications and related signaling...
7.
Auwercx J, Kischel P, Lefebvre T, Jonckheere N, Vanlaeys A, Guenin S, et al.
Cells
. 2022 Jul;
11(14).
PMID: 35883700
Pancreatic diseases, such as pancreatitis or pancreatic ductal adenocarcinoma, are characterized by the presence of activated pancreatic stellate cells (PSCs). These cells represent key actors in the tumor stroma, as...
8.
Goujon M, Woszczyk J, Gaudelot K, Swierczewski T, Fellah S, Gibier J, et al.
Cancers (Basel)
. 2022 Feb;
14(3).
PMID: 35159062
Clear cell renal cell carcinoma (ccRCC) is the main histotype of kidney cancer, which is typically highly resistant to conventional therapies and known for abnormal lipid accumulation. In this context,...
9.
Kumemura M, Pekin D, Menon V, Van Seuningen I, Collard D, Tarhan M
Micromachines (Basel)
. 2021 Dec;
12(12).
PMID: 34945396
The adaptability of microscale devices allows microtechnologies to be used for a wide range of applications. Biology and medicine are among those fields that, in recent decades, have applied microtechnologies...
10.
Boukrout N, Souidi M, Lahdaoui F, Duchene B, Neve B, Coppin L, et al.
Cancers (Basel)
. 2021 Dec;
13(24).
PMID: 34944818
Background: Pancreatic adenocarcinoma (PDAC) is a deadly cancer with an extremely poor prognosis. MUC4 membrane-bound mucin is neoexpressed in early pancreatic neoplastic lesions and is associated with PDAC progression and...