Isabelle Fremaux
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Explore the profile of Isabelle Fremaux including associated specialties, affiliations and a list of published articles.
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21
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Recent Articles
1.
Kempf K, Capello Y, Melhem R, Lescoat C, Kempf O, Cornu A, et al.
ACS Chem Biol
. 2023 Nov;
18(12):2495-2505.
PMID: 37948120
The ellagitannins vescalagin and vescalin, known as actin-dependent inhibitors of osteoclastic bone resorption, were mounted onto chemical probes to explore their interactions with bone cell proteins by means of affinity-based...
2.
Alonso F, Dong Y, Li L, Jahjah T, Dupuy J, Fremaux I, et al.
Proc Natl Acad Sci U S A
. 2023 May;
120(23):e2221742120.
PMID: 37252964
Fibrillin-1 is an extracellular matrix protein that assembles into microfibrils which provide critical functions in large blood vessels and other tissues. Mutations in the fibrillin-1 gene are associated with cardiovascular,...
3.
Dong Y, Alonso F, Jahjah T, Fremaux I, Genot E
Methods Mol Biol
. 2023 Jan;
2608:345-364.
PMID: 36653717
Angiogenesis is the formation of new blood vessels from the existing vasculature. It is a fundamental process in developmental biology but also a pathological event that initiates or aggravates many...
4.
Alonso F, Li L, Fremaux I, Reinhardt D, Genot E
Biomolecules
. 2022 Oct;
12(10).
PMID: 36291539
Fibrillin-1 is an extracellular matrix protein that assembles into microfibrils that provide critical functions in large blood vessels and other tissues. Mutations in the fibrillin-1 gene are associated with cardiovascular,...
5.
Dong Y, Alonso F, Jahjah T, Fremaux I, Grosset C, Genot E
Cell Mol Life Sci
. 2022 Mar;
79(4):208.
PMID: 35347477
Angiogenesis involves cell specification orchestrated by regulatory interactions between the vascular endothelial growth factor and Notch signaling pathways. However, the role of microRNAs in these regulations remains poorly explored. Here...
6.
Alonso F, Spuul P, Decossas M, Egana I, Curado F, Fremaux I, et al.
Eur J Cell Biol
. 2020 May;
99(4):151084.
PMID: 32439218
Invadosomes are specialised actin-based dynamic microdomains of the plasma membrane. Their occurrence has been associated with cell adhesion, matrix degrading and mechanosensory functions that make them crucial regulators of cell...
7.
Georgess D, Spuul P, Clainche C, Le Nihouannen D, Fremaux I, Dakhli T, et al.
Eur J Cell Biol
. 2018 Oct;
97(8):533-545.
PMID: 30287085
Actin subunits assemble into actin filaments whose dynamics and three-dimensional architectures are further regulated by a variety of cellular factors to establish the functional actin cytoskeleton. The C-glucosidic ellagitannin vescalagin...
8.
Spuul P, Daubon T, Pitter B, Alonso F, Fremaux I, Kramer I, et al.
Cell Rep
. 2016 Oct;
17(2):484-500.
PMID: 27705796
During angiogenic sprouting, endothelial tip cells emerge from existing vessels in a process that requires vascular basement membrane degradation. Here, we show that F-actin/cortactin/P-Src-based matrix-degrading microdomains called podosomes contribute to...
9.
Daubon T, Spuul P, Alonso F, Fremaux I, Genot E
J Cell Sci
. 2016 May;
129(13):2586-98.
PMID: 27231093
Podosomes are dynamic cell-matrix contact structures that combine several key abilities, including adhesion, matrix degradation and mechanosensing. These actin-based cytoskeletal structures have been mostly studied in monocytic cells, but much...
10.
Miot C, Beaumont E, Duluc D, Le Guillou-Guillemette H, Preisser L, Garo E, et al.
Gut
. 2014 Sep;
64(9):1466-75.
PMID: 25183206
Objective: Interleukin-26 (IL-26) is a member of the IL-10 cytokine family, first discovered based on its peculiar expression by virus-transformed T cells. IL-26 is overexpressed in chronic inflammation (rheumatoid arthritis...