Isabelle Coppens
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Explore the profile of Isabelle Coppens including associated specialties, affiliations and a list of published articles.
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149
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10581
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Recent Articles
11.
Coppens I, Ward H
Trends Parasitol
. 2023 May;
39(7):499-500.
PMID: 37150658
Invasive Cryptosporidium sporozoites contain organelles that secrete unique proteins to facilitate invasion and remodeling of the infected cell. By identifying a novel secretory organelle, 'small granules', and defining the global...
12.
Romano P, Akematsu T, Besteiro S, Bindschedler A, Carruthers V, Chahine Z, et al.
Autophagy Rep
. 2023 Apr;
2(1).
PMID: 37064813
Pathogenic protists are a group of organisms responsible for causing a variety of human diseases including malaria, sleeping sickness, Chagas disease, leishmaniasis, and toxoplasmosis, among others. These diseases, which affect...
13.
Giuliano C, Wei K, Harling F, Waldman B, Farringer M, Boydston E, et al.
bioRxiv
. 2023 Mar;
PMID: 36945434
Within a host, pathogens encounter a diverse and changing landscape of cell types, nutrients, and immune responses. Examining host-pathogen interactions in animal models can therefore reveal aspects of infection absent...
14.
Romano J, Mayoral J, Guevara R, Rivera-Cuevas Y, Carruthers V, Weiss L, et al.
J Cell Sci
. 2023 Jan;
136(4).
PMID: 36718630
Intracellular pathogens exploit cellular resources through host cell manipulation. Within its nonfusogenic parasitophorous vacuole (PV), Toxoplasma gondii targets host nutrient-filled organelles and sequesters them into the PV through deep invaginations...
15.
Antunes A, Shahinas M, Swale C, Farhat D, Ramakrishnan C, Bruley C, et al.
bioRxiv
. 2023 Jan;
PMID: 36711883
Sexual reproduction of , which is restricted to the small intestine of felids, is sparsely documented, due to ethical concerns surrounding the use of cats as model organisms. Chromatin modifiers...
16.
Cortina M, Bishop R, DeVasure B, Coppens I, Derre I
PLoS Pathog
. 2022 Sep;
18(9):e1010818.
PMID: 36084160
All Chlamydia species are obligate intracellular bacteria that undergo a unique biphasic developmental cycle strictly in the lumen of a membrane bound compartment, the inclusion. Chlamydia specific Type III secreted...
17.
Ende R, Murray R, DSpain S, Coppens I, Derre I
Elife
. 2022 Jul;
11.
PMID: 35838228
Membrane contact sites (MCS) are crucial for nonvesicular trafficking-based interorganelle communication. Endoplasmic reticulum (ER)-organelle tethering occurs in part through the interaction of the ER resident protein VAP with FFAT motif-containing...
18.
Mayoral J, Guevara R, Rivera-Cuevas Y, Tu V, Tomita T, Romano J, et al.
mBio
. 2022 Jun;
13(4):e0144222.
PMID: 35730903
The intracellular parasite Toxoplasma gondii adapts to diverse host cell environments within a replicative compartment that is heavily decorated by secreted proteins. In an attempt to identify novel parasite secreted...
19.
Gubbels M, Ferguson D, Saha S, Romano J, Chavan S, Primo V, et al.
Front Cell Infect Microbiol
. 2022 May;
12:882166.
PMID: 35573773
The Apicomplexa are famously named for their apical complex, a constellation of organelles at their apical end dedicated to invasion of their host cells. In contrast, at the other end...
20.
Hartman E, Asady B, Romano J, Coppens I
Mol Biol Cell
. 2022 Mar;
33(5):ar34.
PMID: 35274991
After mammalian cell invasion, the parasite multiplies in a self-made membrane-bound compartment, the parasitophorous vacuole (PV). We previously showed that interacts with many host cell organelles, especially from recycling pathways,...