Isabelle Carpentier
Overview
Explore the profile of Isabelle Carpentier including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
1078
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Recent Articles
11.
Verhelst K, Verstrepen L, Carpentier I, Beyaert R
Biochem Pharmacol
. 2013 Jan;
85(7):873-80.
PMID: 23333767
The innate immune system forms our first line of defense against invading pathogens and relies for a major part on the activation of two transcription factors, NF-κB and IRF3. Signaling...
12.
Galle M, Carpentier I, Beyaert R
Curr Protein Pept Sci
. 2013 Jan;
13(8):831-42.
PMID: 23305368
Pseudomonas aeruginosa is a dangerous pathogen particularly because it harbors multiple virulence factors. It causes several types of infection, including dermatitis, endocarditis, and infections of the urinary tract, eye, ear,...
13.
Verhelst K, Carpentier I, Kreike M, Meloni L, Verstrepen L, Kensche T, et al.
EMBO J
. 2012 Oct;
31(19):3845-55.
PMID: 23032186
Linear polyubiquitination of proteins has recently been implicated in NF-κB signalling and is mediated by the linear ubiquitin chain assembly complex (LUBAC), consisting of HOIL-1, HOIP and Sharpin. However, the...
14.
Maelfait J, Roose K, Bogaert P, Sze M, Saelens X, Pasparakis M, et al.
PLoS Pathog
. 2012 Mar;
8(3):e1002570.
PMID: 22396652
The innate immune response provides the first line of defense against viruses and other pathogens by responding to specific microbial molecules. Influenza A virus (IAV) produces double-stranded RNA as an...
15.
Verhelst K, Carpentier I, Beyaert R
Cytokine Growth Factor Rev
. 2011 Nov;
22(5-6):277-86.
PMID: 22119011
TNF is a multifunctional cytokine that plays a key role in innate immunity by inducing the expression of a variety of genes that are involved in an inflammatory response. TNF-induced...
16.
Verhelst K, Verstrepen L, Carpentier I, Beyaert R
Biochem Pharmacol
. 2011 Jul;
82(9):1057-65.
PMID: 21787758
Despite its small size, ubiquitin is one of the most versatile signaling molecules in the cell and affects distinct cellular processes. It forms the building block of a repertoire of...
17.
Verstrepen L, Verhelst K, Carpentier I, Beyaert R
Trends Biochem Sci
. 2011 May;
36(7):347-54.
PMID: 21546252
The innate immune system senses and protects against invading microorganisms and endogenous danger signals by triggering inflammatory and antimicrobial responses. However, dysregulation of these pathways, which involve the transcription factors...
18.
Verstrepen L, Verhelst K, van Loo G, Carpentier I, Ley S, Beyaert R
Biochem Pharmacol
. 2010 Jul;
80(12):2009-20.
PMID: 20599425
A20 (also known as TNFAIP3) is a cytoplasmic protein that plays a key role in the negative regulation of inflammation and immunity. Polymorphisms in the A20 gene locus have been...
19.
Verstrepen L, Carpentier I, Verhelst K, Beyaert R
Biochem Pharmacol
. 2009 May;
78(2):105-14.
PMID: 19464428
ABINs have been described as three different proteins (ABIN-1, ABIN-2, ABIN-3) that bind the ubiquitin-editing nuclear factor-kappaB (NF-kappaB) inhibitor protein A20 and which show limited sequence homology. Overexpression of ABINs...
20.
Verhelst K, Verstrepen L, Coornaert B, Carpentier I, Beyaert R
Methods Mol Biol
. 2009 Apr;
517:205-15.
PMID: 19378032
Although Toll-like receptor (TLR)-induced expression of several proinflammatory genes is required to provoke an efficient immune response, excessive or prolonged activation of TLR signaling can contribute to the development of...