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Isabelle Bougie

Explore the profile of Isabelle Bougie including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 292
Followers 0
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Recent Articles
11.
Benzaghou I, Bougie I, Picard-Jean F, Bisaillon M
FEBS Lett . 2006 Jan; 580(3):867-77. PMID: 16413541
The West Nile virus (WNV) RNA genome harbors the characteristic methylated cap structure present at the 5' end of eukaryotic mRNAs. In the present study, we report a detailed study...
12.
Benzaghou I, Bougie I, Bisaillon M
J Biol Chem . 2004 Sep; 279(48):49755-61. PMID: 15375162
The RNA polymerase activity of the hepatitis C virus, a major human pathogen, has previously been shown to be supported by metal ions. In the present study, we report a...
13.
Bougie I, Parent A, Bisaillon M
Biochem J . 2004 Aug; 384(Pt 2):411-20. PMID: 15307816
RNA-capping enzymes are involved in the synthesis of the cap structure found at the 5'-end of eukaryotic mRNAs. The present study reports a detailed study on the thermodynamic parameters involved...
14.
Bougie I, Bisaillon M
J Biol Chem . 2004 Mar; 279(21):22124-30. PMID: 15037606
The broad spectrum antiviral nucleoside ribavirin displays activity against a variety of RNA and DNA viruses. A number of possible mechanisms have been proposed during the past 30 years to...
15.
Bougie I, Bisaillon M
J Biol Chem . 2003 Oct; 278(52):52471-8. PMID: 14563844
Ribavirin is a broad spectrum antiviral nucleoside that displays activity against a variety of RNA and DNA viruses. Ribavirin is currently used in combination with interferon-alpha for the treatment of...
16.
Bisaillon M, Bougie I
J Biol Chem . 2003 Jun; 278(36):33963-71. PMID: 12819229
The Saccharomyces cerevisiae RNA triphosphatase (Cet1) requires the presence of metal ion cofactors to catalyze its phosphohydrolase activity, the first step in the formation of the 5'-terminal cap structure of...
17.
Bougie I, Charpentier S, Bisaillon M
J Biol Chem . 2002 Nov; 278(6):3868-75. PMID: 12458224
The hepatitis C virus nonstructural 5B protein (NS5B) protein has been shown to require either magnesium or manganese for its RNA-dependent RNA polymerase activity. As a first step toward elucidating...