Isabel A English
Overview
Explore the profile of Isabel A English including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
8
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Recent Articles
1.
Link J, Eng J, Pelz C, MacPherson-Hawthorne K, Worth P, Sivagnanam S, et al.
Nat Cancer
. 2025 Jan;
6(1):123-144.
PMID: 39789181
Patients with metastatic pancreatic ductal adenocarcinoma survive longer if disease spreads to the lung but not the liver. Here we generated overlapping, multi-omic datasets to identify molecular and cellular features...
2.
Tinsley S, Chianis E, Shelley R, Mall G, Dhiman A, Baral G, et al.
Oncogene
. 2024 Oct;
43(50):3673-3687.
PMID: 39443726
Oncogenic mutations in KRAS are present in ~95% of patients diagnosed with pancreatic ductal adenocarcinoma (PDAC) and are considered the initiating event of pancreatic intraepithelial neoplasia (PanIN) precursor lesions. While...
3.
Shah V, English I, Sears R
Trends Pharmacol Sci
. 2020 Jul;
41(9):595-597.
PMID: 32624198
In cancer, suppression of protein phosphatases, such as protein phosphatase 2A (PP2A), that normally counteract kinases, contributes to aberrant signaling. Leonard et al. recently demonstrated that a novel small-molecule activator...
4.
English I, Sears R
Cancer Discov
. 2020 Apr;
10(4):495-497.
PMID: 32238397
In this issue of , Sodir and colleagues employ a pancreatic ductal adenocarcinoma mouse model with mutant KRAS and inducible MYC to demonstrate that MYC acts as a reversible driver...