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Irtisha Singh

Explore the profile of Irtisha Singh including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 711
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Recent Articles
1.
Wang T, Sawhney S, Morgan D, Bennett R, Rashmi R, Estecio M, et al.
Proc Natl Acad Sci U S A . 2024 Sep; 121(39):e2403062121. PMID: 39302966
The progression of many solid tumors is accompanied by temporal and spatial changes in the stiffness of the extracellular matrix (ECM). Cancer cells adapt to soft and stiff ECM through...
2.
Singh K, Soukar J, Zulkifli M, Kersey A, Lokhande G, Ghosh S, et al.
Nat Commun . 2024 Sep; 15(1):8136. PMID: 39289340
Diminished mitochondrial function underlies many rare inborn errors of energy metabolism and contributes to more common age-associated metabolic and neurodegenerative disorders. Thus, boosting mitochondrial biogenesis has been proposed as a...
3.
Modaresi S, Pacelli S, Chakraborty A, Coyle A, Luo W, Singh I, et al.
Adv Healthc Mater . 2024 Aug; 13(29):e2401264. PMID: 39152923
Human adipose-derived stem cells (hASCs) are cryopreserved traditionally using dimethyl sulfoxide (DMSO) as the cryoprotectant agent. DMSO penetrates cell membranes and prevents cellular damage during cryopreservation. However, DMSO is not...
4.
Singh I, Rainusso N, Kurenbekova L, Nirala B, Dou J, Muruganandham A, et al.
Mol Cancer Res . 2024 Jun; 22(9):864-878. PMID: 38842581
Osteosarcoma is the most common primary malignant bone tumor affecting the pediatric population with a high potential to metastasize. However, insights into the molecular features enabling its metastatic potential are...
5.
Murali A, Brokesh A, Cross L, Kersey A, Jaiswal M, Singh I, et al.
Adv Sci (Weinh) . 2024 May; 11(29):e2402468. PMID: 38738803
Minerals play a vital role, working synergistically with enzymes and other cofactors to regulate physiological functions including tissue healing and regeneration. The bioactive characteristics of mineral-based nanomaterials can be harnessed...
6.
Kersey A, Singh I, Gaharwar A
Acta Biomater . 2024 Mar; 183:371-386. PMID: 38552761
Inorganic biomaterials have been shown to direct cellular responses, including cell-cell and cell-matrix interactions. Notably, ions released from these inorganic biomaterials play a vital role in defining cell identity, and...
7.
Kersey A, Cheng D, Deo K, Dubell C, Wang T, Jaiswal M, et al.
Biomaterials . 2024 Feb; 306:122473. PMID: 38335719
Engineered matrices provide a valuable platform to understand the impact of biophysical factors on cellular behavior such as migration, proliferation, differentiation, and tissue remodeling, through mechanotransduction. While recent studies have...
8.
Singh I, Rainusso N, Kurenbekova L, Nirala B, Dou J, Muruganandham A, et al.
bioRxiv . 2023 Nov; PMID: 38014160
Osteosarcoma (OS) is the most common primary malignant bone tumor affecting the pediatric population with high potential to metastasize to distal sites, most commonly the lung. Insights into defining molecular...
9.
Gaharwar A, Singh I
Nat Mater . 2023 Mar; 22(4):412-413. PMID: 36928384
No abstract available.
10.
Joddar B, Loyola C, Ramirez S, Singh I
Biochem Biophys Res Commun . 2023 Feb; 648:72-80. PMID: 36736094
Hyperglycemia-mediated cardiac dysfunction is an acute initiator in the development of vascular complications, leading to cardiac fibrosis. To investigate the effects of hyperglycemia-mediated changes in cardiomyocytes, cells were cultured in-vitro...